Liver Function Test-1 (Maxi)

• LFT are used to assess function of liver which may be altered during liver infections, non-infectious conditions or injury. 
• Measure the levels of liver enzymes in case of liver diseases like fatty liver, cirrhosis, alcoholic hepatitis, or jaundice.
• LFT can be used to monitor progression of diseases i.e., viral or alcoholic hepatitis, and their response to treatment
• It is also done to monitor side effects of medications i.e., Isoniazid, Rifampicin & Pyrazinamide treatment for tuberculosis

Liver Function Test-1 (Maxi) measures:

• Prothrombin Time (PT)
• Bilirubin-Total, Direct & Indirect
• Serum Glutamic Oxaloacetic Transaminase (SGOT)
• Serum Glutamic Pyruvic Transaminase (SGPT)
• Gamma-Glutamyl Transferase (GGTP)
• Proteins
• Alkaline Phosphatase (ALP)
• Lactate Dehydrogenase (LDH)

Liver Profile test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

Ideally all parameters should be within the biological reference range. High levels are associated with certain diseases.

• High ALT is associated with liver damage
• High AST is associated with liver, muscle or other organ damage or disease. In isolated liver damage rise in ALT n AST is disproportionate to ALP 
• High ALP is associated with blocked bile duct, or certain bone diseases and rise in such conditions is disproportionate to AST & ALT
• Low proteins may be associated with liver disease or damage
• High bilirubin might indicate liver damage (increase in direct bilirubin) or disease or certain types of anaemia (increase in indirect bilirubin)
• High GGT may indicate bile duct damage. It may increase in hepatitis, liver cancer, and acute heart conditions. But together with ALP can help pinpoint liver-related disorders
• High Prothrombin time may be due to deficiency of coagulation factors or deficiency of Vitamin K or anticoagulants being administered
• LDH is increased in Hodgkin's disease, multiple myeloma and diseases involving blood (megaloblastic & pernicious anaemia), heart, liver, lung, kidney and other organs

There are no specific preparations required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

Bilirubin is measured in milligrams per decilitre of blood. A value less than 1.2 mg/dl is normal.

Bilirubin - Direct: 0.0 to 0.3 mg/dL

Bilirubin - Total: 0.0 to 1.2 mg/dL

AST: 8 to 48 U/L

ALT: 7 to 55 U/L

Total Proteins: 6.3 to 7.9 g/dL

Albumin: 3.5 to 5 g/dL

ALP: 40 to 129 U/L

These are the ranges of test values for adults.

• Avoid smoking
• Avoid drinking alcohol
• Lose the excessive weight
• Regularly exercise
• Drink coffee
• Avoid junk foods high in cholesterol
• Increase folic acid-rich foods

Warning signs of a liver ailment include -

• yellow skin and eyes
• abdominal pain and swelling
• chronic weakness
• dark urine
• pale-coloured stools
• Itching of the skin
• swelling in ankles and feet

• LFT
• Liver Panel
• Liver Chemistries
• Liver Function Panel
• Liver Profile
• Prothrombin Time
• Bilirubin Total
• Bilirubin Direct
• Bilirubin Indirect
• Serum Glutamic-oxaloacetic Transaminase (SGOT)
• Aspartate Transaminase (AST)
• Serum Glutamic-pyruvic Transaminase (SGPT)
• Alanine Transaminase (ALT)
• Gamma Glutamyl Transpeptidase (GGTP)
• Proteins
• Alkaline Phosphatase (ALP)
• Lactate Dehydrogenase (LDH)

People with the following medical conditions should do the liver function maxi test:

• Diabetes
• Liver Cancer
• Wilson's Disease
• Hemochromatosis
• Toxic Hepatitis
• Jaundice
• Hepatitis A, B, and C
• Cirrhosis
• Fatty Liver
• Alcoholic Hepatitis
• Non-alcoholic Hepatitis
• Hemochromatosis. 

Doctors advise the liver function maxi test for people with lifestyle issues such as:

• alcohol
• obesity
• tattoos
• piercings
• blood transfusion
• unprotected exposure to other people's blood or body fluids like semen, urine, or sweat
• type 2 diabetes mellitus