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Thrombophilia Profile-Maxi
53+ booked in last 3 days
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 48 Hours
Blood test at Home
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Thrombophilia Profile-Maxi Details in Brief
| Also Known As | Hypercoagulable State Profile, Thrombophilia Panel |
|---|---|
| Purpose | To check for conditions that increase the risk of abnormal blood clots |
| Preparation | No Specific Preparation required |
| Fasting | Does not require fasting |
| Reporting Time | Within 1 Week |
| Cost | 18,500 |
Thrombophilia Profile Test Overview
The "Thrombophilia Profile-Maxi" is an extensive panel of tests used to evaluate and diagnose various thrombophilic conditions, which are disorders that increase the risk of abnormal blood clot formation (thrombosis). The profile includes a comprehensive set of coagulation and immune-related tests to assess different factors involved in the clotting process and immune responses that can contribute to thrombotic events. The key components of the Thrombophilia Profile-Maxi include:
- Protein C: Measures the level and activity of Protein C, a natural anticoagulant that helps regulate blood clotting. Low levels of Protein C may increase the risk of clot formation.
- Protein S: Measures the level and activity of Protein S, another natural anticoagulant protein that assists Protein C in controlling clotting. Deficiencies in Protein S can lead to a prothrombotic state.
- Antithrombin III (AT-III): Measures the level of AT-III, a critical inhibitor of coagulation factors. Deficiencies in AT-III can result in increased clotting tendencies.
- Activated Protein C Resistance (APCR): Tests for resistance to activated protein C, which can indicate the presence of a genetic mutation that is associated with an increased risk of clotting.
- Lupus Anticoagulant: Detects the presence of antibodies that interfere with the normal clotting process, leading to a tendency towards thrombosis.
- Homocysteine: Measures the level of homocysteine, an amino acid. Elevated homocysteine levels are associated with an increased risk of blood clots.
- Beta-2 Glycoprotein 1 (IgG / IgM): Detects antibodies against beta-2 glycoprotein 1, which may be linked to autoimmune-related clotting disorders.
- ACA (Anticardiolipin Antibodies) (IgG / IgM): Detects anticardiolipin antibodies, which are also associated with autoimmune-mediated clotting events.
The Thrombophilia Profile-Maxi is ordered when there is suspicion of an underlying thrombophilia, recurrent blood clots, unexplained thrombotic events, or a family history of thrombosis. It provides a comprehensive assessment of various clotting factors and immune-related markers to aid in the diagnosis and management of thrombophilic conditions. Based on the test results, healthcare providers can devise personalized treatment plans to prevent or manage thrombotic events and reduce the risk of complications.
Reasons for Undergoing the Thrombophilia Profile
The thrombophilia profile is a comprehensive blood test used to assess an individual's risk of developing abnormal blood clots. It helps identify genetic or acquired conditions that increase the likelihood of thrombosis. This test is often recommended for those with a history of clotting disorders, recurrent thrombosis, or pregnancy-related complications.
Here's a detailed list of reasons why this crucial diagnostic tool would be recommended by doctors:
- Evaluation of Unexplained Thrombosis: To identify the underlying cause of unexplained or recurrent venous thromboembolism (VTE), especially in young individuals or those without obvious risk factors.
- Family History: If there is a family history of thrombophilia or recurrent thrombotic events, testing can help determine if family members are at risk.
- Recurrent Thrombosis: To investigate the cause of recurrent thrombotic events, which could indicate an underlying thrombophilic condition.
- Unusual Thrombosis Sites: When thrombosis occurs in unusual sites, such as the mesenteric, hepatic, portal, or cerebral veins, thrombophilia testing is warranted.
- Pregnancy Complications: To evaluate women with a history of recurrent miscarriages or other pregnancy complications that may be associated with thrombophilia, particularly antiphospholipid syndrome (APS).
- Risk Assessment and Management: To guide treatment decisions, such as the type and duration of anticoagulation therapy, and to assess the risk of future thrombotic events.
List of Parameters Considered During the Thrombophilia Profile
The thrombophilia profile includes several tests to evaluate different components of the blood's clotting system:
- Antithrombin (AT): Measures the level of antithrombin, a protein that inhibits the activity of several clotting factors. Low levels indicate a deficiency, which can increase the risk of thrombosis.
- Protein C: Assesses the level of protein C, another anticoagulant protein. Low levels suggest a deficiency, which increases the risk of venous thrombosis.
- Protein S: Evaluates the level of protein S, which works with protein C to inhibit clotting factors. Low levels indicate a deficiency, increasing the risk of venous thrombosis.
- Lupus Anticoagulant: Tests for the presence of lupus anticoagulant, an antibody associated with antiphospholipid syndrome (APS), which is linked to an increased risk of both venous and arterial thrombosis.
- Anticardiolipin Antibodies (ACA): Measures the levels of IgG and IgM anticardiolipin antibodies, also associated with APS and an increased risk of thrombosis.
- Activated Protein C Resistance (APCR) and Factor V Leiden: Tests for resistance to activated protein C and the presence of the factor V Leiden mutation, a common inherited thrombophilia.Anti Beta-2-Glycoprotein-1 Antibodies: Tests for the presence of anti-beta-2-glycoprotein-1 IgG and IgM antibodies, also linked to APS and an increased risk of thrombosis.
- Prothrombin Gene Mutation (G20210A): Tests for the prothrombin gene mutation, another inherited thrombophilia that increases the production of prothrombin, a clotting factor, leading to an increased risk of venous thrombosis.
Home Collection for Thrombophilia Profile Near You
Metropolis Healthcare offers a convenient home collection service for the thrombophilia profile test, making diabetes management easier without compromising on quality. A trained phlebotomist will visit your home to collect a sample, focusing on your comfort and safety while following strict sample handling guidelines. You can expect prompt and accurate results, enabling you to take proactive steps in managing your health. With Metropolis Healthcare’s commitment to accessible and high-quality diagnostic solutions, you can trust us for your thrombophilia profile testing needs from the comfort of your home. Experience a seamless testing process with Metropolis Healthcare's home collection service and know your thrombotic risk factors.
Thrombophilia Profile-Maxi Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Thrombophilia Profile-Maxi with a clear pricing structure. The Thrombophilia Profile-Maxi Price in Mumbai is ₹ 18,500. We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The Thrombophilia Profile evaluates the Antigen and Activity of Protein C, Protein S, AT-III, APCR, Lupus Anticoagulant, Homocysteine, Beta-2 Glycoprotein 1 (IgG/ IgM), ACA (IgG/ IgM).
- To evaluate your risk of developing abnormal blood clots (thrombosis)
- To investigate recurrent miscarriages or pregnancy-related complications
- To assess the effectiveness of anticoagulant therapy
- To diagnose and monitor thrombophilia (inherited or acquired)
- To guide prevention strategies for individuals at high risk of thrombosis
The Thrombophilia Profile may be recommended if you have:
- a personal or family history of blood clots
- recurrent miscarriages or pregnancy complications
- unexplained thrombosis at a young age
- a history of thrombosis while on anticoagulant treatment
- an autoimmune disorder associated with an increased risk of thrombosis, or
- a planned surgery or treatment that may increase the risk of blood clots
Abnormal results could indicate a higher risk of developing abnormal blood clots.
Blood samples will be collected from your vein. The sample will be sent to the laboratory for testing.
There are no specific preparations required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.
- D-Dimer: This blood test helps detect the presence of a blood clot.
- Factor V Leiden Mutation Test: This genetic test identifies a common inherited mutation associated with an increased risk of abnormal blood clot formation.
- Prothrombin Gene Mutation Test: This genetic test identifies a mutation in the prothrombin gene, which can increase the risk of abnormal blood clot formation.
Hypercoagulable State Profile or Thrombophilia Panel
Thrombophilia refers to a tendency to develop abnormal blood clots. It can be caused by inherited genetic mutations, acquired conditions, or a combination of both. Thrombophilia increases the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other clotting disorders.
Thrombophilia profile is a set of blood tests that helps identify individuals with an increased tendency to form blood clots due to inherited or acquired conditions. It evaluates various components of the blood's clotting system to determine the presence of thrombophilic disorders.
The thrombophilia profile is essential for identifying individuals at high risk of thrombotic events, guiding treatment decisions, and assessing the need for long-term anticoagulation therapy. It helps manage and prevent recurrent thrombosis, particularly in those with a family history or unexplained thrombotic events.
Yes, thrombophilia is a blood disorder characterised by an increased tendency to form blood clots. It can be caused by either inherited genetic mutations or acquired factors, affecting the blood's clotting mechanism and leading to hypercoagulability.
During pregnancy, a thrombophilia profile test may be recommended for women with a history of recurrent miscarriages, stillbirths, or other pregnancy complications that could be associated with thrombophilic conditions. The test helps identify antiphospholipid syndrome (APS) or other thrombophilias that may require anticoagulation therapy during pregnancy.
The benefits of a thrombophilia profile include identifying the underlying causes of unexplained or recurrent thrombosis, guiding anticoagulation therapy and management, assessing the risk of future thrombotic events, enabling family screening to identify at-risk individuals, and aiding in the prevention of pregnancy complications in women with thrombophilia.
Fasting is generally not required for the thrombophilia profile tests. However, it is essential to follow the specific instructions provided by your healthcare professional to ensure accurate results.
Thrombophilia is diagnosed through a combination of clinical evaluation and laboratory tests, including the thrombophilia profile. The test results, along with the patient's medical history and physical examination, help healthcare professionals determine the presence and type of thrombophilic disorder.
Yes, many diagnostic laboratories, including Metropolis Healthcare, offer home sample collection services for the thrombophilia profile. This convenient option allows individuals to have their blood samples collected by trained phlebotomists in the comfort of their homes, ensuring a safe and hassle-free experience.
The turnaround time for thrombophilia profile reports usually takes 24 hours to 1 week depending on the day/time the sample is collected and processed.
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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