Anti-CCP Antibody (Cyclic Citrullinated Peptide Antibody) Test
55+ booked in last 3 daysCCP Antibody Test Overview
Rheumatoid Arthritis (RA) is an autoimmune disease which affects joints. RA is a chronic, inflammatory disease that mainly affects the hands and feet, thereby causing pain, swelling, and stiffness in the joints. Patients exhibit clinical manifestations like joint erosion, interstitial lung disease and cardiovascular disease. Delayed diagnosis of RA is associated with joint disease and poor outcomes. Anti-CCP antibodies are useful in early diagnosis of patients suspected of Rheumatoid arthritis and its severity. The CCP antibodies test is often done along with the rheumatoid factor (RF) test, but the RF can even be found in healthy people. Thus, the CCP test provides a more accurate diagnosis of the disease.
Reasons for Undergoing the Anti-CCP Test
The anti-CCP test is a valuable diagnostic tool used primarily to diagnose and manage rheumatoid arthritis (RA). Here are the key reasons for undergoing this test:
- Diagnosing Rheumatoid Arthritis (RA): The anti-CCP test is particularly useful in confirming the presence of RA, especially when symptoms indicate an inflammatory arthritis. It helps differentiate RA from other types of arthritis, such as osteoarthritis, gout, or psoriatic arthritis, ensuring an accurate diagnosis.
- Differentiating from Other Arthritis Types: Although osteoarthritis and gout can present symptoms similar to rheumatoid arthritis (RA), the anti-CCP test is a useful tool for differentiating between these conditions. Its specificity to RA, making it an important part of diagnosing the condition.
- Assessing Disease Severity: The anti-CCP test can also predict the potential severity and progression of RA. Higher level of anti-cyclic citrullinated peptide antibodies are often linked to a more aggressive or erosive form of the disease, helping healthcare providers tailor treatments accordingly.
- Early Detection: One of the main benefits of the test is an early detection of RA, even before symptoms are visible. This allows for an earlier treatment and better strategies to manage the disease.
- Treatment Monitoring: The anti-CCP test is also used to monitor the effectiveness of treatments, guiding adjustments to therapy for optimal management of RA.
Reasons for Undergoing the Anti-CCP Test
The anti-CCP test is a valuable diagnostic tool used primarily to diagnose and manage rheumatoid arthritis (RA). Here are the key reasons for undergoing this test:
- Diagnosing Rheumatoid Arthritis (RA): The anti-CCP test is particularly useful in confirming the presence of RA, especially when symptoms indicate an inflammatory arthritis. It helps differentiate RA from other types of arthritis, such as osteoarthritis, gout, or psoriatic arthritis, ensuring an accurate diagnosis.
- Differentiating from Other Arthritis Types: Although osteoarthritis and gout can present symptoms similar to rheumatoid arthritis (RA), the anti-CCP test is a useful tool for differentiating between these conditions. Its specificity to RA, making it an important part of diagnosing the condition.
- Assessing Disease Severity: The anti-CCP test can also predict the potential severity and progression of RA. Higher level of anti-cyclic citrullinated peptide antibodies are often linked to a more aggressive or erosive form of the disease, helping healthcare providers tailor treatments accordingly.
- Early Detection: One of the main benefits of the test is an early detection of RA, even before symptoms are visible. This allows for an earlier treatment and better strategies to manage the disease.
- Treatment Monitoring: The anti-CCP test is also used to monitor the effectiveness of treatments, guiding adjustments to therapy for optimal management of RA.
List of Parameters Considered During the Anti-CCP Test
The anti-CCP blood test primarily measures one key parameter. This parameter and its implications are as follows:
Anti-cyclic citrullinated peptide (anti-CCP) antibodies: These autoantibodies target cyclic citrullinated peptides, and their presence and levels are measured in units called EU/mL (units per milliliter).
- Negative results (less than 20 EU/mL) suggest the absence of significant levels of ACPAs.
- Weakly positive results (20-39 EU/mL) may indicate early stages of RA or a lower risk of severe disease.
- Moderately positive results (40-59 EU/mL) suggest an increased risk of RA.
- Strongly positive results (more than 60 EU/mL) are highly predictive of rheumatoid arthritis and may suggest a more severe and progressive form of the disease.
Home Collection for Anti-CCP Test Near You
At Metropolis Healthcare, we understand the importance of convenience and accessibility when it comes to healthcare. That’s why we provide a hassle-free home sample collection service for the anti-CCP antibody test. Our trained phlebotomists will visit your home to collect the blood sample, ensuring you are comfortable and safe.
We adhere to strict standards for sample handling and testing accuracy, ensuring that you can trust the reliability of your results. With our commitment to deliver quality diagnostic solutions and making healthcare more accessible, you can expect a prompt and accurate results from the comfort of your home. Choose Metropolis Healthcare for a seamless and dependable anti-CCP test experience.
Anti-CCP Antibody (Cyclic Citrullinated Peptide Antibody) Test Price
Anti-CCP Antibody (Cyclic Citrullinated Peptide Antibody) Test Price Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Anti-CCP Antibody (Cyclic Citrullinated Peptide Antibody) Test with a clear pricing structure. The Anti-CCP Antibody (Cyclic Citrullinated Peptide Antibody) Test Price in Mumbai is ₹ 1,720. We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
- CCP antibody test aids in the diagnosis of rheumatoid arthritis, particularly in early stages when symptoms may not be definitive.
- Higher levels of CCP antibodies may indicate a more severe and progressive form of RA, helping in prognosis and treatment planning.
- Helps differentiate RA from other autoimmune conditions that may present similar symptoms.
- Early detection through CCP antibody testing allows for prompt initiation of treatment, potentially slowing down disease progression and minimizing joint damage.
- Serial CCP antibody testing can help monitor disease activity and treatment response in patients with RA.
This test measures the presence of CCP antibodies in the blood of patients with or estimated to have rheumatoid arthritis.
During CCP antibody test blood sample is taken from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.
20 units/ml is considered the normal level of CCP antibodies. Test results above 20 units/ml are considered to be positive.
-
Rheumatoid Arthritis (RA): A positive CCP antibody test is highly specific for RA, meaning it's more likely to indicate RA than other conditions. If you have symptoms of RA like joint pain, swelling, and stiffness, a positive test result strengthens the possibility of RA.
-
Early RA or Increased Risk: A positive CCP test result, especially with negative rheumatoid factor (another blood test for RA), might suggest you're in the early stages of RA or have an increased risk of developing it in the future.
-
Other Conditions: While less common, positive CCP tests can occur with other inflammatory diseases like lupus or Sjogren's syndrome.
The CPP antibody test can also come positive in the case of the following diseases:
- Osteoarthritis
- Chronic liver disease
- SLE (Systemic lupus erythematosus)
- Psoriatic arthritis
- Seronegative arthritis
- Sjogren's syndrome
- Systemic sclerosis
A blood sample is taken for the test, just like other tests. You may feel dizzy, lightheaded, or have soreness at the site of blood collection, however, there is nothing inherently dangerous about the test itself.
What other types of tests are ordered in addition to the CCP antibody test for rheumatoid arthritis?
In addition to the CPP antibody test, the doctor may suggest the following tests as sometimes it’s difficult to detect the disease in its early stages:
- RF test
- X-ray of joints
- Erythrocyte sedimentation rate (ESR)
- C-reactive protein
- Antinuclear antibody
- Synovial fluid analysis
It is the most common form of arthritis in which the protective cartilage that surrounds the joints wears down or changes in structure.
Connective tissue disorders are a type of autoimmune disease like rheumatoid arthritis, scleroderma, lupus, microscopic polyangiitis, Marfan syndrome, Churg-Strauss syndrome, polymyositis/dermatomyositis and Granulomatosis with polyangiitis (GPA).
It’s a group of arthritis that shows similar symptoms to rheumatoid arthritis such as joint pains, swelling, and tenderness in the joints along with morning stiffness that lasts for almost an hour.
- CCP Antibody
- Anti-Citrulline Antibody
- Citrulline Antibody
- Anti-CCP Test
- ACPA
- Anti-Cyclic Citrullinated Peptide
- Citrullinated Antibody
People with the following symptoms should do the CCP Antibody Serum Test:
- Low-grade fever
- Joint, back, or muscle pain
- Stiffness of the joints, especially in the morning
- Fatigue
- Joint swelling, tenderness, or weakness
- Malaise
- Lumps or redness of the skin
- Bump on fingers
- Sensation of pins and needles
- Dry mouth
- Flare
- Physical deformity
- Swelling of hands
The anti-CCP test is a blood test that detects and measures levels of anti-cyclic citrullinated peptide antibodies (ACPAs) in the blood, which are associated with rheumatoid arthritis (RA). The anti-CCP blood test helps to diagnose RA, assess severity, and predict progression.
The anti-CCP test is important for an early detection of rheumatoid arthritis, even before symptoms are visible. It differentiates RA from other arthritis types, assesses severity, guides treatment, and improves outcomes by enabling early intervention.
A high level of CCP antibodies is usually indicated by values greater than 60 EU/mL. This strongly positive anti-CCP test result is highly predictive of rheumatoid arthritis and suggests a higher risk of developing a more severe and progressive form of the disease.
The benefits of anti-CCP test includes early detection of RA, differentiating it from other types of arthritis, assessment disease severity and progression, guidance for treatment planning, monitoring treatment effectiveness, and potential identification of at-risk individuals before symptom onset.
No, fasting is not required before the anti-CCP blood test. patients should make sure to inform their healthcare provider about any medications, herbs, vitamins, or supplements they are taking.
Elevated levels of CCP antibodies detected by the anti-CCP test are mainly linked to rheumatoid arthritis (RA), indicating a more severe or an aggressive form of disease. In rare cases, elevated anti-cyclic citrullinated peptide levels can be seen in other autoimmune conditions, such as systemic lupus erythematosus (SLE) and psoriatic arthritis, but they are most strongly linked to RA.
It’s not possible to lower anti-CCP levels solely through lifestyle changes. Managing rheumatoid arthritis (RA) including treatment options such as medications, lifestyle modifications, and regular monitoring by a healthcare provider, which are helpful in managing the condition and may lower antibody levels over time.
Yes, home sample collection is available for the anti-CCP test. Many diagnostic labs, including Metropolis Healthcare, provides convenient home collection services. This allows patients to have their blood samples taken at home without needing to visit a clinic, making it easier to get tested for rheumatoid arthritis and related conditions.
Usually, results for the anti-CCP blood test are ready within 6 hours, though this can vary based on when the sample is collected and processed.
Ratings & Reviews (0)
Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.