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VGKC - CSF & Serum in Byculla
50+ booked in last 3 days
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Sample Type
Blood
Recommended for
Male, Female
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Within 24 Hours
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Overview
Voltage-Gated Potassium Channel (VGKC) antibodies (predominately Anti-LGI1 and Anti-CASPR2) are associated with paraneoplastic neurological syndromes and limbic encephalitis.
Autoimmune encephalitis is a debilitating inflammatory disorder of the brain causing various neurological signs and symptoms. VGKCs are proteins consisting of - Leucine-rich glioma inactivated protein 1(LGI1) & Contactin-associated protein 2 (CASPR2), responsible for controlling the cell membrane potential; development of antibodies against these proteins can cause Morvan syndrome, epilepsy and limbic encephalitis (short memory loss, psychiatric symptoms). These antibodies may also be associated with certain types of tumours.
Total tests included :2 tests [Antibodies to LGI1 and CASPR2]
Written by : Dr.Shibani R Medical Writer Medical Affairs
VGKC - CSF & Serum Price in Byculla
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the VGKC - CSF & Serum with a clear pricing structure
The price of VGKC - CSF & Serum in Byculla is ₹ 14,175
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
For differential diagnosis of Paraneoplastic Neurological Syndrome, Autoimmune Encephalitis, Neuromyotonia.
This test is performed for patients suspected of suffering from nervous system disorders which are of autoimmune origin.
Voltage-Gated Potassium Channel (VGKC) antibodies (predominately Anti-LGI1 and Anti-CASPR2) are associated with paraneoplastic neurological syndromes and limbic encephalitis. These antibodies may also be found in other conditions such as acquired neurmyotonia, painful neuropathy, Morvan's syndrome, and rare tumors (eg, thymoma, small-cell lung cancer). This indirect fluorescent antibody assay utilizes LGI1 and CASPR2 transfected cell lines for the detection and semi-quantification of autoantibodies. Sensitivity is improved when CSF is tested along with serum for detection of antibodies.
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Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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