Vitamin D Plus Profile

• This test is a helpful indication of osteomalacia, rickets, and osteoporosis (bone weakening).
• Rickets in toddlers and osteomalacia in adults, which manifests as bone malformation and raises the risk of fracture, must be diagnosed through testing.
• Estimated levels are used to track vitamin D replacement therapy.
• Secondary hyperparathyroidism can be identified by low vitamin D levels.
• PTH test is used to identify hyperparathyroidism and hypoparathyroidism, and to track renal disease along with vitamin D levels.
• PTH is also employed in the diagnosis of kidney stones and osteoporosis causes.
• Vitamin D plus test is done in cases of abnormal calcium levels. This may mainly occur in patients with chronic kidney diseases, where the vitamin D levels are suspected to be affected due to faulty metabolism.
• It may be done to diagnose any genetic predisposition to vitamin D deficiency. 

Vitamin D Plus Profile measures the level of 1,25 Dihydroxy vitamin D in the blood. PTH test is done when Vit D is less than 30 ng/ml.

A vitamin D plus profile is a blood test. During a blood test, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Low levels may occur in chronic renal impairments and also in cases of hypoparathyroidism. High levels may occur in hyperparathyroidism or due to certain diseases like sarcoidosis and lymphomas. 

Low vitamin D levels are linked to osteoporosis, brittle bones, and a higher risk of fractures. Rickets can result from severe deficiency. Very high levels are linked to weakness, poor appetite, constipation, nausea, and vomiting.

If Vitamin D becomes less than 30 ng/ml, a PTH test is performed.

If your doctor believes you have too much or not enough vitamin D, they will order a 25-hydroxyvitamin D test. The chance for vitamin D deficiency may be monitored with a 25-hydroxyvitamin D test.

The following people are at a high risk of vitamin D deficiency -

1. Breastfeeding babies
2. Older people
3. Overweight adults
4. People who have undergone gastric bypass surgery
5. People who do not get a lot of sun exposure
6. Those with gastrointestinal disorders, like inflammatory bowel disease, make it challenging for the body to process nutrition
7. Individuals with darker skin

Several further tests can be added to the vitamin profile exam package in addition to the ones mentioned above, including:

• TSH or thyroid-stimulating hormone
• Ionized calcium
• Magnesium
• Folic acid or folates
• Vitamin A
• Beta-carotene
• Vitamin K

While there typically aren't specific requirements for a Vitamin D Plus profile, it's always best to consult your doctor or healthcare provider for any specific instructions they may have. They can advise you on any medications or supplements to avoid beforehand and answer any questions you may have about the test.

Rickets is a disease that leads to softening and distortion of bones. It is caused by a severe deficiency in vitamin D.

An illness in which the bones become fragile and brittle due to loss of tissue t is called osteoporosis. The pelvis, spine, and wrist bones, in particular, weaken over life and become more susceptible to fracture (breaking). It usually occurs due to calcium or Vitamin D deficiency and hormonal changes.

Osteomalacia is a serious vitamin D shortage that results in a noticeable softening of your bones.

• 25-hydroxy Vitamin D (25(OH)D)
• PrathParathyroidone (PTH)
• Vit D reflex PTH