Home Visit
Upload
Tumor Mutation Burden NGS
Also known as: NextGen Tumor Mutation Burden Panel by NGS, FFPE Tissue**
No special precautions
Recommended for
Male, Female
Report
Within 4 Weeks
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
Overview
Mutations are changes in the DNA sequence that can occur in cancer cells. Mutations can affect how cancer cells grow, multiply, and respond to treatment. NextGen Tumor Mutation Burden (TMB) is a genomic biomarker used to measure the total number of genetic mutations within the tumor cells of a cancer patient. TMB is assessed through next-generation sequencing techniques that analyze the tumor's DNA and identify the presence of various genetic alterations, including single nucleotide variants, insertions, deletions, and structural variations. The higher the number of mutations detected, the higher the TMB score. TMB serves as an indicator of the overall mutational burden within a tumor and can help predict the likelihood of response to immunotherapy treatments, such as immune checkpoint inhibitors. Patients with high TMB scores are more likely to exhibit an increased number of neoantigens, which can stimulate an immune response against the tumor. Therefore, TMB assessment plays a crucial role in guiding treatment decisions and identifying patients who may benefit from immunotherapy-based approaches.
NextGen Tumor Mutation Burden Panel by NGS, FFPE Tissue** Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the NextGen Tumor Mutation Burden Panel by NGS, FFPE Tissue** with a clear pricing structure.
The NextGen Tumor Mutation Burden Panel by NGS, FFPE Tissue** Price in Mumbai is ₹ 43,000 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The Tumour Mutation Burden Test measures the number of genetic mutations in a tumour sample. It helps identify specific genetic changes that may be driving the growth and spread of cancer cells.
- To identify specific genetic mutations that help determine targeted therapies
- To assess the effectiveness of treatment options
- To predict the response to immunotherapy
- To guide decisions for clinical trials and research studies
The Tumour Mutation Burden Test is recommended in the following situations:
- When other diagnostic tests suggest the presence of cancer
- When considering immunotherapy as a treatment option
- For research purposes to study individual genetic profiles
Results from the Tumour Mutation Burden Test are not considered abnormal or normal. They provide information about specific gene mutations present in the tumour sample.
A small sample of the tumour tissue is collected during a biopsy or surgery. The sample is sent to a laboratory for genetic analysis through next-generation sequencing (NGS) technology.
- Provide your doctor with your genetic history and any relevant medical records.
- Inform your doctor if you have any specific requirements.
- Histopathological examination of the tumour sample to provide additional information about the type and stage of cancer
- Molecular studies to identify specific gene mutations that can impact treatment options
- Genetic testing to assess inherited risk factors or potential targets for therapy
TMB Test or Genetic Mutation Analysis
Cancer is a disease characterised by the uncontrolled growth and spread of abnormal cells in the body. It can occur in any organ or tissue and is caused by genetic mutations that disrupt normal cell regulation.
Ratings & Reviews (0)
Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
WhatsApp