Tacrolimus By LCMS, Blood Test

This test measures the therapeutic level of the drug Tacrolimus in the blood.

• To monitor the therapeutic level of Tacrolimus and optimize its dosage for organ transplant patients • To ensure that Tacrolimus is within the desired range for effective suppression of the immune system • To prevent toxic side effects associated with high levels of Tacrolimus in the body

• Organ transplant recipients to monitor drug levels and adjust dosage as needed • Patients experiencing signs of rejection, such as fever, pain, or abnormal lab results • Patients who have recently started or changed their Tacrolimus medication • Individuals at risk for Tacrolimus toxicity due to factors like age, kidney function, or interacting medications

High levels may indicate potential for toxicity or increased risk of side effects. Low levels may suggest inadequate immunosuppression and risk of transplant rejection.

This test involves drawing a small sample of blood from a vein in your arm using a needle and a syringe. You may feel a slight pinch as the needle is inserted, but the procedure is generally quick and painless.

• Inform your doctor about all medications, including supplements, you are currently taking. • Follow any specific instructions from your doctor regarding medication timing. • No fasting or dietary restrictions are necessary before this test. Please reach out to your healthcare provider for any specific requirements.

• Creatinine: Measures kidney function, as Tacrolimus is cleared by the kidneys. • Liver function tests: Assess liver health as the liver metabolizes Tacrolimus. • Complete blood count: Determines overall blood health and can help identify potential side effects of Tacrolimus.

Tacrolimus therapeutic drug monitoring (TDM), Tacrolimus level test

Transplant rejection is a process in which a transplant recipient's immune system treats the new transplanted organ or tissue like a foreign object and attacks it. Tacrolimus is a medication belonging to a class of drugs called immunosuppressants. It works by suppressing the immune system's response to the transplanted organ, reducing the risk of rejection and allowing successful transplantation.