Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing in Khokhdadad

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Sample Type

Blood

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Male, Female

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Test Overview

Beta-globin gene (HBB) sequencing is used to identify hemoglobin variants and common beta thalassemia sequence variants, including β+ β0. In addition point mutations related to HbS/ HbE/ HbD/ HbC are also detected
Gene sequencing test is done when abnormal hemoglobin presence is suspected by the treating physician after review of Hb electrophoresis & red cell indices results
Depending upon the type of mutation a patient may suffer from decrease synthesis of hemoglobin or complete absence. Patients with complete absence suffer from thalassemia major and consequently from serious form of disease; in contrast thalassemia intermedia have decreased production of hemoglobin and suffer from a milder from of disease

The two most prevalent beta-thalassemia lineages, beta plus and beta zero thalassemias, can be found via beta-globin gene (HBB) sequencing. Additionally, it identifies dominant beta-thalassemia sequence changes and hyper-unstable haemoglobin variations. This method can be used to find additional haemoglobin variations that protein-based methods are unable to find.

This test is performed when your doctor detects the existence of aberrant haemoglobin after reviewing the red cell index and haemoglobin electrophoresis results. Depending on the mutation, haemoglobin is either completely absent or may be present at low levels. Thalassemia major is a severe condition since the patients cannot produce haemoglobin. People with thalassemia intermedia, on the other hand, produce less haemoglobin and have a milder form of the disease.

Who Should Do the Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing?

HBB test is recommended for individuals with:

Clinical findings of anaemia and splenomegaly.
Family history of thalassemia or hemoglobinopathy.
Persistent haemolytic anaemia of unknown origin.
Abnormal results on haemoglobin evaluation by electrophoresis or high-performance liquid chromatography (HPLC).
Abnormal results on the complete blood count (CBC) test.
Abnormal DNA tests for alpha and beta globins.

Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs

Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing Price in Rajkot

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing with a clear pricing structure

The price of Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing in Rajkot is ₹ 9,680

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Why take Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing?

To identify hemoglobin variants and the most common beta thalassemia sequence variants.

Is this test for you?

This profile is for individuals to identify hemoglobin variants and the most common beta thalassemia sequence variants.

More Info on Beta-Thalassemia, Beta Globin (HBB) Gene Sequencing

This test can identify hemoglobin variants and the most common beta thalassemia sequence variants.

How it Works?

All our phlebotomists are vaccinated

At Metropolis Healthcare, your well-being is our top priority. Rest assured, all our skilled phlebotomists are vaccinated, ensuring a safe and secure experience for you. Our team upholds the highest healthcare standards, and your health is in capable hands. Your safety is non-negotiable, and at Metropolis, we take every measure to guarantee it.

Our Phlebotomists maintain a high standard of safety precautions

Our dedicated team of phlebotomists prioritises your safety before anything else. They implement stringent safety measures to guarantee your well-being during their visit.

Strictly adhering to aseptic techniques, our phlebotomists maintain a sterile environment with thorough sanitization and the use of gloves, masks and face shields. Needles are disposed of with utmost care, following rigorous guidelines to minimise any potential risks. We leave no room for compromise when it comes to personal protective equipment (PPE), ensuring both you and our staff are well protected.

Our phlebotomists collect samples safely

The phlebotomists at Metropolis Healthcare are proficient in safe sample collection. They skillfully and gently draw blood, minimizing any discomfort you may feel. We prioritize your safety by using sterile, single-use needles and barcoded vials to completely eliminate any risk of cross-contamination. Our collection area is carefully sanitized before, during, and after your sample collection.

Samples are processed at high-tech facilities

Metropolis Healthcare takes pride in its state-of-the-art facilities, where your samples are thoroughly processed. Our labs are equipped with cutting-edge machinery with advanced technology, eliminating chances of human error. From the moment your sample arrives at our facility, it undergoes an automated process.

Your samples are stored in clean and secure facilities

We leave no room for compromise when it comes to the storage of your samples. Our storage facilities are regularly cleaned and disinfected, upholding the highest standards of healthcare safety.

Temperature-controlled environments and cooling facilities ensure that your samples remain fresh and the results produced are accurate. Our cutting-edge security measures prevent unauthorized access, guaranteeing the confidentiality of your health data.

Metropolis provides accurate digital reports

Our advanced sample processing machines not only deliver swift results to you but also generate precise digital reports. We provide conclusive diagnoses through meticulous re-checks and repeat specimen analyses, if required, at no extra cost, adding an extra layer of accuracy and dependability. This unique approach sets us apart, earning the trust of top doctors and hospitals across the country.

Your health is our priority, and we spare no effort in our commitment to providing you with the most accurate insights you can rely on.

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Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.