PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow

50+ booked in last 3 days

No special precautions

Sample Type

Blood

Recommended for

Male, Female

Report

Within 24 Hours

Blood test at Home

NABL & CAP Accredited Labs

Accurate & Quality Test Reports

Trusted by Leading Doctors & Hospitals

Overview

The "PV panel (Jak-2 V617F Reflex to Jak-2 Exon 12 Mutation)-Bone Marrow" test is a diagnostic tool used to investigate suspected cases of Polycythemia Vera (PV) through bone marrow analysis. The test utilizes Real Time PCR and Sanger Sequencing methods to detect specific mutations in the Jak-2 gene. It begins by screening for the Jak-2 V617F mutation, which is commonly associated with PV. If the initial Jak-2 V617F test is negative or inconclusive, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV. Detecting these mutations in the bone marrow helps in confirming the diagnosis of PV, a condition characterized by the overproduction of red blood cells, and allows for timely and appropriate management of the disease.

PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow with a clear pricing structure.

The PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow Price in Khanna is ₹ 6,720 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

What does PV Panel measure?

PV Panel screens for the Jak-2 V617F mutation firts. If the initial Jak-2 V617F test is negative or inconclusive, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV.

Why is PV Panel done?

• To detect and confirm cases of Polycythemia Vera • To evaluate patients with symptoms such as excessive red blood cell production, increased blood thickness, and enlarged spleen • To differentiate Polycythemia Vera from other similar conditions

When is PV Panel recommended and who should take the test?

• PV Panel is recommended when Polycythemia Vera is suspected based on symptoms like fatigue, headaches, dizziness, or an enlarged spleen. • People with a family history of Polycythemia Vera or those with unexplained high haemoglobin or hematocrit levels may also be advised to take this test.

What if the results of the PV Panel are abnormal?

An abnormal PV Panel result may indicate the presence of genetic mutations associated with Polycythemia Vera.

What to expect during the PV Panel - bone marrow?

During the PV Panel, a healthcare professional will collect a small sample of bone marrow from you after giving you local anaesthesia. They will send the sample to the laboratory for analysis.

What preparations are required before the PV Panel?

• Discuss any medications or supplements you are taking with your doctor, as some may affect the test results. • Inform your doctor if you have any specific requirements.

What other tests may be ordered with PV Panel?

• Complete Blood Count (CBC): This test helps evaluate the overall composition and health of blood cells • JAK2 Mutation Analysis: Detects a specific genetic mutation commonly associated with Polycythemia Vera • Erythropoietin Level: Measures the hormone erythropoietin, which is involved in red blood cell production

What is the PV Panel also known as?

Polycythemia Vera panel or Polycythemia Vera genetic test

What is Polycythemia Vera?

Polycythemia Vera is a rare blood disorder characterised by the overproduction of red blood cells in the bone marrow. This leads to an increase in viscosity, which can cause complications such as blood clots, bleeding problems, and an enlarged spleen.

Ratings & Reviews (0)

No reviews available

Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.