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PV Panel Test (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation)-Blood
50+ booked in last 3 days
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Sample Type
Blood
Recommended for
Male, Female
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Within 24 Hours
Blood test at Home
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Overview
Polycythemia Vera (PV) is a rare blood disorder caused by a genetic mutation in the JAK2 gene. The JAK2 mutation is present in majority of the people with PV. The "PV panel (Jak-2 V617F Reflex to Jak-2 Exon 12 Mutation)-Blood" is designed to diagnose Polycythemia Vera (PV), a myeloproliferative neoplasm characterized by the overproduction of red blood cells. The clinical utility of this test lies in its application for suspected cases of PV. It involves first screening for the Jak-2 V617F mutation, which is commonly associated with PV. If the initial Jak-2 V617F test is negative, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV. Detecting these mutations in the blood aids in confirming the diagnosis of PV and allows for timely and appropriate management of the condition.
PV Panel Test (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation)-Blood Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PV Panel Test (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation)-Blood with a clear pricing structure.
The PV Panel Test (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation)-Blood Price in Mumbai is ₹ 8,480 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
PV Panel analyzes specific genetic mutaions in JAK2 V617F. If the initial Jak-2 V617F test is negative, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV.
• To detect and confirm cases of Polycythemia Vera • To differentiate between different types of myeloproliferative neoplasms (MPN) • To provide crucial information for treatment planning and monitoring disease progression
Your doctor may recommend PV Panel if • you have symptoms such as increased blood cell production, enlarged spleen, or abnormal blood counts, • you have a family history of MPN or known genetic risk factors, or • you have already been diagnosed with MPN and need further characterisation of the subtype for proper management.
Abnormal results indicate the need for further evaluation and consultation with a haematologist or oncologist.
During the test, a small amount of blood (3–5 ml) will be drawn from a vein in your arm. The blood sample will then be sent to the laboratory for analysis.
• Inform your doctor about any medications you are taking, as certain drugs might affect the test results. Also, tell them if you have any specific requirements. • Follow any specific instructions provided by your doctor regarding fasting, if necessary.
Depending on your specific case, your doctor may recommend the following additional tests to further evaluate and monitor your condition: • Complete Blood Count (CBC) • Bone Marrow Biopsy • Additional genetic testing such as JAK2 V617F allele burden assessment
Polycythemia Vera Genetic Testing or Genetic Analysis for Polycythemia Vera
Polycythemia Vera is a rare blood disorder characterised by the overproduction of red blood cells. This condition leads to an increased risk of blood clots, bleeding, and other complications. It is caused by genetic mutations in the bone marrow cells responsible for blood cell production.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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