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JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR in Pune
51+ booked in last 3 days
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 1 Week
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
JAK2 Mutation Test Overview
The JAK-2 (Janus kinase 2) mutation, specifically the V617F variant, detected by Real-Time PCR, is notably associated with myeloproliferative disorders, collectively known as chronic myeloproliferative disorders (CMPD). This genetic mutation plays a pivotal role in the dysregulation of hematopoietic stem cell proliferation, leading to the overproduction of blood cells. Real-Time PCR, a highly sensitive molecular diagnostic technique, enables the detection of the JAK-2 V617F mutation in a patient's genomic DNA, aiding in the diagnosis and classification of CMPDs such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Identifying the JAK-2 mutation by Real-Time PCR holds significant clinical relevance, helping clinicians tailor treatment strategies and monitor disease progression, ultimately improving the management of patients with these hematological disorders.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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