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PRA Identification Class I and Class II

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Overview

PRA Identification by Luminex is a test that assesses the presence and strength of antibodies in a recipient's blood against specific human leukocyte antigens (HLA) in both Class I and Class II. The Class I component evaluates the recipient's immune response to Class I HLA antigens, which are expressed on most nucleated cells, while the Class II component focuses on Class II HLA antigens primarily found on immune cells. By analyzing the recipient's antibody-antigen interactions using Luminex technology, the test provides valuable information about the level of sensitization and compatibility between the recipient and potential organ or tissue donors. Higher PRA levels in either Class I or Class II indicate a higher likelihood of pre-existing antibodies that may lead to immune-related complications following transplantation. This information aids transplant teams in making informed decisions regarding donor selection, cross-matching, and the development of personalized immunosuppressive strategies to minimize the risk of rejection and optimize transplant outcomes.

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PRA Identification Class I and Class II Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PRA Identification Class I and Class II with a clear pricing structure.

The PRA Identification Class I and Class II Price in Mumbai is ₹ 19,080 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The PRA (panel-reactive antibody) test identifies HLA antibodies in both Class I and Class II that are present in your blood.

• To assess the risk of organ transplant rejection • To determine the immunological compatibility between a donor and a recipient • To monitor the effectiveness of immunosuppressive therapy and evaluate autoimmune conditions

Your doctor may recommend this test if • you need an organ transplant, • you have previously received a transplant, or • you have an autoimmune disease and require immunosuppressive therapy.

The presence of HLA antibodies in your blood indicates a high risk of transplant rejection. Abnormal results may also indicate autoimmune diseases such as lupus or rheumatoid arthritis.

• During this test, a small amount of blood will be drawn from a vein in your arm. • The sample will then be sent to the laboratory for testing.

• Your doctor may advise you to avoid certain medications or supplements that can interfere with your test results. • You should also inform your doctor about any medical conditions or specific requirements you may have.

• Cross-matching: to determine the compatibility between a donor and a recipient. • HLA typing: to identify the HLA antigens present in your cells.

Panel Reactive Antibody (PRA) Test or Pre-transplant cross-matching test

Organ transplant rejection occurs when your immune system identifies the transplanted organ as foreign and attacks it. This can lead to complications or failure of the transplant, requiring additional medical procedures to manage or remove the transplanted organ.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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