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HLA B27 Test (Human Leucocyte Antigen B27) in Panvel
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Blood
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Male, Female
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Within 48 Hours
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HLAB27 Test Overview
Human leukocyte antigen HLA-B27 is a MHC (major histocompatibility complex) class I surface antigen encoded by the B locus on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammatory bowel disease, and reactive arthritis. HLA B27 is considered to be an important criterion for the classification of axial spondyloarthropathies & helps in establishing early diagnosis of ankylosing spondyloarthropathies before the development of irreversible deformities. HLA-B27 is present in approximately 89% of patients with ankylosing spondylitis, 79% of patients with Reiter syndrome, and 42% of patients with juvenile rheumatoid arthritis. However, it is not diagnostic for these disorders. Approximately 8% of the normal population carries the HLA-B27 antigen.
Written by: Dr. Sanjay Gohil, MBBS, M.D, Dept. of Haematology
HLA B27 Test (Human Leucocyte Antigen B27) Price in Panvel
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the HLA B27 Test (Human Leucocyte Antigen B27) with a clear pricing structure
The price of HLA B27 Test (Human Leucocyte Antigen B27) in Panvel is ₹ 2,450
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
Autoimmune disorders like ankylosing spondylitis, reactive arthritis is progressive in nature. Symptoms typically start in the early 30’s but effects are visually seen on an x-ray after many years. The symptoms start out subtle and gradually develop over the years. This test helps determine whether you have human leukocyte antigen B27 (HLA-B27) on the surface of your cells and in turn it helps assess the likelihood that you may be suffering from an autoimmune disorder.
The doctor may order the test for you if you display the following symptoms
- Pain, inflammation associated with stiffening of spine, neck and chest may indicate ankylosing spondylitis.
- Inflammation of the joints and skin lesions
HLA-B27 is a specific protein that is found on cell surfaces. The HLAB27 is used to identify the presence or absence of this protein on white blood cells. The full form of HLA is Human Leukocyte Antigen and helps the body identify between its own cells and foreign body. People with HLA-B27 have an increased likelihood of developing autoimmune diseases such as ankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis and isolated acute anterior uveitis. HLAB27 is also associated with Inflammatory Bowel Disease.
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