Ovarian Reserve Profile-Mini Test

The Ovarian Reserve Profile-Mini measures the AMH and Inhibin B levels in the blood.

• Used as a marker for male and female infertility evaluation
• Indicator of low ovarian reserve in perimenopausal women
• Monitoring of patients with ovarian tumors/residual ovarian cancer or relapse after treatment
• Aids in the diagnosis of granulosa cell tumors and mucinous epithelial ovarian tumors

People with the following symptoms:

• Patients with symptoms of menstrual irregularities
• Those with abnormal sexual characteristics
• Females with difficulties conceiving to know the ovarian stimulation.
• Those at risk for pituitary or hormone dependant tumours.
• Patients with anorchia, testicular failure, menopause, precocious puberty.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

No special precautions.

AMH [Anti-Mullerian Hormone] Inhibiting Substance

High levels are seen in Polycystic ovarian syndrome, irregular menstrual cycles, Granulosa cell tumor and in menopause.

 Low levels indicate reduced ovarian reserve

Inhibin B test

Inhibin B levels cannot be used as the only test to assess infertility. Results are age and sex dependent and need to be correlated with other test results and clinical findings.

High Inhibin B levels in women may indicate ovarian malignancies and need to be correlated with clinical features. High levels in pregnant women indicate foetal abnormalities. 

Elevations of inhibin B after treatment are suggestive of residual, recurrent, or progressive disease. In patients with recurrent disease, inhibin B elevation seems to be present earlier than clinical symptoms. Inhibin B levels are typically higher in men with normal fertility.

Low levels in women in child-bearing group may indicate problems in conceiving.

Low levels in men indicate low sperm count.

At menopause, serum inhibin B decrease to very low or undetectable levels.

 For monitoring of patients with known ovarian cancer, inhibin B levels decrease to very low or undetectable levels shortly after surgery.

• Ovarian Test
• AMH test
• Inhibin B test

AMH is a hormone produced by testis in males and by ovarian follicles till antral stage. In males it is used to evaluate testicular presence and function. In females it is often used to check a woman's ability to produce eggs that can be fertilized for pregnancy.

Inhibin B is a reproductive hormone responsible for the production of eggs in females and sperm in men. Inhibin B gives an idea about the ovarian reserve and hence is useful in the diagnosis of infertility in males and females.