Newborn Screening 8 Analytes Neoxpert 8 Profile Test

Neoxpert 8 measures the levels of TSH (Thyroid stimulating hormone), G6PD (Glucose-6-phosphate dehydrogenase), 17 OH Progesterone, Phenyl Alanine, Cystic Fibrosis, Galactosemia, Biotinidase, and MSUD (Maple syrup urine disease) in a newborn's blood sample.

• To identify and treat metabolic disorders early on
• To prevent severe health complications associated with these disorders
• To help doctors formulate appropriate treatment plans

Neoxpert 8 test is recommended for all newborns between the ages of 48 hours and 5 days. It is particularly important if

• the baby has a family history of metabolic disorders or inborn errors of metabolism,
• the baby shows symptoms such as poor feeding, lethargy, vomiting, or seizures, or
• the mother has had metabolic disorders or if there were complications during pregnancy.

If any of the analyte levels are significantly high or low, it may indicate a metabolic disorder or an inborn error of metabolism. Further confirmatory testing will be required, and the child may need treatment.

The Neoxpert 8 test involves collecting a small amount of blood from the baby's heel or finger using a lancet. The blood is then transferred onto filter paper for analysis.

While there are no specific preparations needed, it is advisable to consult your healthcare provider to determine if there are any particular requirements you should be aware of.

• Plasma confirmation test for amino acid and organic acid analysis
• LCMS (liquid chromatography-mass spectrometry) or GCMS (gas chromatography-mass spectrometry) method for confirmation of abnormal analyte levels
• Tandem mass spectrometry and electrospray ionisation for confirmation of abnormal analyte levels

Newborn Screening, NBS

Metabolic disorders or inborn errors of metabolism are genetic conditions that affect how your body processes food into energy. When untreated, they can cause serious health problems such as developmental delays, seizures, and liver or kidney damage.