Leukemia Aml Panel By Fish Test, Leukemic Blood in Mumbai
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Leukemia also known as blood cancer occurs due to abnormal growth and mutations of the white blood cells. This mutation majorly occurs in the bone marrow, but may be seen in the peripheral blood as well. Leukemia cells majorly behave like abnormal WBCs or platelets. Acute Myeloid Leukemia (AML) is the most common type of acute leukemias in adults. If not treated early, the prognosis can be poor. Most cases of AML are associated with genetic mutations. The Leukemia AML panel uses FISH for genotypic and cytogenetic studies of leukemic cells. This helps in further treatment of AML Leukemia.
Written by - Dr.Shibani R, Medical Writer, Medical Affairs
Leukemia Aml Panel By Fish Test, Leukemic Blood Price in Mumbai
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Leukemia Aml Panel By Fish Test, Leukemic Blood with a clear pricing structure
The price of Leukemia Aml Panel By Fish Test, Leukemic Blood in Mumbai is ₹ 15,900
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Frequently Asked Questions
Detecting a neoplastic clone associated with recurrent chromosome abnormalities seen in adult patients with acute myeloid leukemia (AML) or other myeloid malignancies. Conventional chromosome analysis is the gold standard for identification of the common, recurrent chromosome abnormalities in AML. However, some of the subtle rearrangements can be missed by karyotype, including inv(16) and MLL rearrangements.
As suggested by the doctor detecting a neoplastic clone associated with recurrent chromosome abnormalities seen in adult patients with acute myeloid leukemia (AML).
The initial panel includes testing for the following abnormalities using the probes listed:ETO / AML1,PML / RARA,CBFB and MLL by FISH. Several recurrent chromosomal abnormalities have been identified in AML with associated clinical significance. The most common chromosome abnormalities associated with AML include t(8;21), t(15;17), inv(16), and abnormalities of the MLL (KMT2A) gene at 11q23. Overall, the recurrent chromosome abnormalities identified in patients with AML are observed in approximately 60% of diagnostic AML cases. Fluorescence in situ hybridization (FISH) analysis of nonproliferating (interphase) cells can be used to detect the common diagnostic and prognostic chromosome abnormalities observed in patients with AML. When recurrent translocations or inversions are identified, FISH testing can also be used to track response to therapy.
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