MTB Antibiogram Test (TB NGS) by Next Generation Sequencing - Pure Culture

This test detects the mutations in Mycobacterium tuberculosis (MTB) that cause resistance to anti-tuberculosis drugs.

• To identify drug-resistant strains of Mycobacterium tuberculosis in patients with TB • To choose the appropriate antibiotics for treating TB and prevent the development of drug-resistant strains • To guide clinicians in adjusting treatment plans for patients who are not responding to standard TB therapy

This test may be recommended if you • have a confirmed diagnosis of tuberculosis, • have a history of previous TB treatment or exposure to drug-resistant strains, • are not responding to standard TB treatment, or • are at high risk of developing drug-resistant TB due to factors such as close contact with an individual with drug-resistant TB or a history of non-compliance with treatment.

Abnormal results may suggest the need for alternative or modified treatment regimens to effectively treat tuberculosis.

During this test, a sample of your sputum or other respiratory specimen will be collected. This sample to the laboratory for analysis.

• Provide accurate information about your clinical history, including previous TB treatment and exposure to drug-resistant strains. • Follow any instructions given by your doctor regarding discontinuing medications that may interfere with the accuracy of the test. • Inform your doctor if you have any specific requirements.

• Acid-fast bacilli (AFB) smear microscopy: This initial test detects the presence of Mycobacterium tuberculosis in sputum or other respiratory samples. • Culture and drug susceptibility testing (DST): This test determines the presence of TB bacteria and their sensitivity to specific antibiotics.

TB NGS or Mycobacterium tuberculosis Next Generation Sequencing

Tuberculosis (TB) is a contagious bacterial infection caused by Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other organs. TB spreads through the air when an infected individual coughs or sneezes. Symptoms include persistent cough, weight loss, fatigue, and fever.