Levetiracetam

This test measures the levels of levetiracetam, an antiepileptic drug, in your blood.

This test is done for the following reasons:

• To monitor and adjust the dosage of levetiracetam to ensure optimal seizure control
• To detect and monitor potential side effects or toxicity related to levetiracetam
• To assess medication compliance in patients taking levetiracetam regularly
• To evaluate possible drug-drug interactions with other medications being taken alongside levetiracetam.

This test may be recommended for individuals who:

• Have been diagnosed with epilepsy and are prescribed levetiracetam as part of their treatment regimen
• Experience persistent seizures despite being on a regular dose of levetiracetam
• Show signs or symptoms of drug toxicity such as dizziness, confusion, or difficulty coordinating movements
• Are taking other medications that may interact with levetiracetam, potentially affecting its effectiveness

The normal therapeutic range for levetiracetam in the blood is generally between 12 and 46 micrograms per milliliter (mcg/mL). Low levels of levetiracetam could suggest poor compliance with medication or inadequate dosage for seizure control. High levels of levetiracetam may indicate potential toxicity and increased risk of side effects. Discuss your results with your doctor who will interpret them in the context of your medical history and other diagnostic tests.

• A small sample of your blood will be taken from a vein in your arm using a needle
• The procedure is relatively quick and involves minimal discomfort
• You may experience mild bruising or soreness at the site where the blood was drawn
• The sample will be sent to a laboratory for analysis using a method called LCMSMS

• Follow your doctor's instructions regarding taking your medication before the test.
• Inform your doctor about any other medications or supplements you are taking.
• You may be asked to fast for a few hours before the test, although this depends on your doctor's instructions.

• Liver function tests: To assess the health and function of the liver, as levetiracetam is primarily metabolised by the liver
• Kidney function tests: To evaluate the kidney's ability to filter waste products, as levetiracetam is eliminated from the body through the kidneys

Levetiracetam Blood test or Serum Keppra test

Epilepsy is a neurological disorder characterised by recurrent seizures. Seizures occur due to abnormal electrical activity in the brain. Epilepsy can result from various factors such as genetics, brain injuries, or certain medical conditions. Management of epilepsy often involves antiepileptic medications like levetiracetam to control seizures and improve quality of life.