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JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR in Kolkata
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Sample Type
Blood
Recommended for
Male, Female
Report
Within 1 Week
Blood test at Home
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JAK2 Mutation Test Overview
The JAK-2 (Janus kinase 2) mutation, specifically the V617F variant, detected by Real-Time PCR, is notably associated with myeloproliferative disorders, collectively known as chronic myeloproliferative disorders (CMPD). This genetic mutation plays a pivotal role in the dysregulation of hematopoietic stem cell proliferation, leading to the overproduction of blood cells. Real-Time PCR, a highly sensitive molecular diagnostic technique, enables the detection of the JAK-2 V617F mutation in a patient's genomic DNA, aiding in the diagnosis and classification of CMPDs such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Identifying the JAK-2 mutation by Real-Time PCR holds significant clinical relevance, helping clinicians tailor treatment strategies and monitor disease progression, ultimately improving the management of patients with these hematological disorders.
JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR Price in Kolkata
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR with a clear pricing structure
The price of JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR in Kolkata is ₹ 6,800
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
To aid diagnose bone marrow disorders called as myeloproliferative neoplasms (MPNs) in which the bone marrow creates too many of one or more types of blood cells.
The JAK2 V617F test is usually recommended by the doctor if he suspects that the patient may be suffering from myeloproliferative neoplasm (MPN). The symptoms include:
- Blood clot in the vein or artery
- Heart attack
- Bleeding
- Problems with vision
- Stroke
- Kidney stones
- Fever
- Breathing problem
The Janus Kinase 2 gene commonly known as the JAK2 provides commands to cells for creating the JAK2 protein. This protein helps promote cell growth and division and is especially crucial for controlling blood cell production inside the bone marrow. The bone marrow disorders caused JAK2 mutations are known as myeloproliferative neoplasms (MPNs) in which the bone marrow produces way too many WBCs, RBCs and Platelets. Some of the MPNs most commonly associated with JAK2 mutations are: Polycythaemia vera, Essential thrombocythemia and Primary myelofibrosis.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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