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Gliadin-IgG Antibodies De-amidated (DGP) Serum Test in Kolhapur

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Gliadin IGG Test Overview

Celiac disease (CD) is an immune-mediated enteropathy induced by dietary gluten. 
When a genetically predisposed individual consumes food containing gluten like  wheat, barley, rye, and other grains ,inflammation and damage of the small bowel mucosa occurs which leads to malabsorption , loss of bone density, miscarriage, infertility or even neurological diseases or certain cancers. Gliadin IGG test is a non invasive , quantitative determination of IgA antibodies against deamidated gliadin protein epitopes (DGP) in human serum or plasma.

Overview

 

Gliadins are proteins present in gluten-containing cereals like wheat, barley, rye, and other grains. IgA and IgG antibodies against gliadins are found in the sera of patients with celiac disease (CD). On reaching the small intestine, transglutaminase deaminates gliadins. This increases the binding of gliadins to MHC class II molecules. Gliadins get attached to these antibodies and damage the small bowel mucosa by triggering inflammation.

 

What is the DGP Serum Test?

The DGP serum test is a non-invasive, quantitative test that detects de-amidated IgG gliadin antibodies in the sera of untreated CD patients. These antibodies are nonspecific for celiac disease. They are also found in other gastrointestinal diseases. However, IgG gliadin antibodies are preferred in children less than 2 years, in people with IgA deficiencies, and in cases of equivocal tTG IgA results.

Written by: Dr Mukilarasi K R, M.D Pathology

 

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Gliadin-IgG Antibodies De-amidated (DGP) Serum Test Price in Kolhapur

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Gliadin-IgG Antibodies De-amidated (DGP) Serum Test with a clear pricing structure

The price of Gliadin-IgG Antibodies De-amidated (DGP) Serum Test in Kolhapur is ₹ 2,140

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Test helps in detection of IgG-Gliadin antibodies for the diagnosis of celiac disease & monitoring adherence to gluten-free diet
Test is done on patient suffering from suspected Celiac disease
Celiac disease antibody tests help diagnose and monitor the disease and a few other gluten-sensitive conditions. These tests detect autoantibodies in the blood that the body produces as part of the immune response. Deamidated gliadin peptide (DGP) antibodies (anti-DGP), IgA or IgG — may be used in some people with suspected celiac disease who are negative for anti-tTG, especially children younger than 2 years old

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