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sFlt-1/PlGF Ratio Serum Test in Kalyan

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Overview

sFlt-1/PlGF ratio is a biomarker used in obstetrics to assess the risk of developing preeclampsia in pregnant women. Preeclampsia is a pregnancy-specific disorder characterized by high blood pressure and proteinuria after 20 weeks of gestation. It is a leading cause of maternal and fetal morbidity and mortality worldwide.

sFlt-1 (soluble fms-like tyrosine kinase-1) is a soluble receptor for vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), which are important for the development and maintenance of the placenta and fetal growth. sFlt-1 binds to VEGF and PlGF, reducing their availability and leading to endothelial dysfunction and vascular damage. PlGF is a growth factor produced by the placenta that promotes angiogenesis and blood vessel growth.

The sFlt-1/PlGF ratio in maternal serum is a biomarker that reflects the balance between sFlt-1 and PlGF levels in circulation. A high sFlt-1/PlGF ratio is associated with an increased risk of developing preeclampsia in pregnant women, particularly in those with suspected or confirmed fetal growth restriction. The ratio can also be used to predict adverse maternal and fetal outcomes, such as preterm birth, low birth weight, and neonatal morbidity and mortality.

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sFlt-1/PlGF Ratio Serum Test Price in Kalyan

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the sFlt-1/PlGF Ratio Serum Test with a clear pricing structure

The price of sFlt-1/PlGF Ratio Serum Test in Kalyan is ₹ 5,800

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

This test allows laboratory to diagnose & predict likelihood of a pregnant female to develop pre-eclampsia .

This test is recommended for pregnant females post 20 weeks of pregnancy. Initial signs of pre-eclampsia are new onset of hypertension and proteinuria.

Test includes testing for Total Testosterone, Albumin , SHBG and finally calculation of bioavailable testosterone by standard algorithm. A number of conditions and medications are known to increase or decrease the SHBG (Sex Hormone-Binding Globulin, Serum) concentration, which may cause bound and available testosterone concentration to change. Bioavailable Testosterone is a good test to evaluate hypogonadism with testosterone concentration at lower limit of normal. It is also useful in the below cases:

  • Inherited abnormalities in SHBG binding
  • Liver disease and severe systemic illness
  • Hyperthyroidism

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