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Lp- PLA2 Test (PLAC)Cardiac Risk Marker Serum in Kalyan

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Lp Pla2 Plac Test Overview

Lp-PLA2 test measures the concentration of Lp-PLA2(lipoprotein - associated phospholipase A2 a vascular-specific inflammatory marker implicated in the formation of rupture-prone plaque. It is a biomarker providing information on risk for atherosclerotic cardiovascular disease (CVD) independent of traditional cardiovascular risk factors. It is produced in the plaque itself. It is vascular specific unlike other inflammatory markers that measure systemic inflammation. 

The Lp-PLA2 (PLAC) Cardiac Risk Marker is a medical test. This test can determine the level of lipoprotein-related phospholipase (Lp-PLA2) in plasma. Lp-PLA2 is an enzyme that is carried by low-density lipoprotein. LDL transports Lp-PLA2 towards the coronary artery walls and triggers an inflammatory reaction here. If this condition is present, the plaque will be more likely to rupture. Therefore, Lp-PLA2 levels above a certain threshold signal an elevated risk of a heart attack or stroke.

Why is the Lp-PLA2 (PLAC) Cardiac Risk Marker Serum test done?

An Lp-PLA2 serum test is advised to determine how inflamed the blood vessels are. Compared to a routine cholesterol check, this provides a more thorough picture of the risk of developing heart disease. This may be done if,

  • There is a family history of heart disease at a young age.
  • High LDL values are discovered despite taking treatment.
  • Hypercholesterolemia runs in the family.
  • Pre-existing blood vessel conditions with normal levels of total cholesterol and triglycerides.
  • Personal history of heart conditions requiring or not requiring surgery.

Written by: Dr.Shibani R, Medical Writer, Medical Affairs

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Lp- PLA2 Test (PLAC)Cardiac Risk Marker Serum Price in Kalyan

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Lp- PLA2 Test (PLAC)Cardiac Risk Marker Serum with a clear pricing structure

The price of Lp- PLA2 Test (PLAC)Cardiac Risk Marker Serum in Kalyan is ₹ 2,500

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

PLAC test is a simple biopsy that assesses your cardiac health. Cholesterol testing alone may fall short to detect a definitive diagnosis and cholesterol test can miss hidden risks for heart attack. Around 50% of heart attacks occur in patients with normal cholesterol; rather most cardiovascular (CV) events i.e., heart attack and strokes are caused due to rupture of plaque that is formed by cholesterol deposition within the blood vessels.

In heart diseases, it's known that an unhealthy lifestyle-such as intake of fatty foods, excess alcohol and smoking have a significant role to play in developing the risk of a stroke. This can shoot up cholesterol levels and increases blood pressure. Blood vessels become clogged with fatty deposits which will dislodge and make their route to the brain, depriving it of oxygen. Despite the fact, the doctors still opine that significant number of events occur in people with no obvious risk factors for the disease, hence measuring these levels is critical. 
Eventually, the unstable plaque can rupture, become potential lethal clots and debris loose in bloodstream—causing a stroke or a heart attack . PLAC test is second generation enzyme linked immunoassay test, helping doctors with prediction of future strokes and heart attack

Your doctor would recommend this test for you if he suspects the risks of cardiovascular diseases or a chance of stroke based on your family history, age, cholesterol levels.

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a blood vessel enzyme, found to be the second most predictive of heart attack risk, also gives indications of plaque that could abruptly precipitate like a volcano. The higher the level of Lp-PLA2, correlates to the corresponding higher risk of cardiac events i.e., heart attack and stroke - even with normal LDL cholesterol.

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