Immunofixation Quantitative Urine Test

The Immunofixation Quantitative Urine test is a medical laboratory test that measures the levels of certain proteins, called immunoglobulins or antibodies, in the urine. It specifically measures the levels of different types of immunoglobulins in the urine, including IgG, IgA, and IgM.

• To diagnose and monitor multiple myeloma: This test can help identify the abnormal protein (M protein) produced by cancerous plasma cells in the bone marrow.
• To detect and monitor other conditions with abnormal protein levels: The test can also detect other conditions, such as monoclonal gammopathy of undetermined significance (MGUS), Waldenstrom macroglobulinemia, and amyloidosis.
• To determine the extent of disease: Quantitative immunofixation can provide information about the amount of M protein present in the urine, which can help determine the extent of disease.
• To evaluate treatment efficacy: The test can be used to monitor the response to treatment and the progression of the disease over time.
• To rule out false positives: The test can help differentiate between a true positive result and a false positive result, which can occur due to certain medications or infections.
• To monitor disease recurrence: If a patient has been treated for multiple myeloma, immunofixation can be used to monitor for disease recurrence.

The following symptoms may indicate the need for an Immunofixation Quantitative Urine test:

• Bone pain, especially in the spine or ribs
• Fatigue and weakness
• Anemia (low red blood cell count)
• High levels of calcium in the blood
• Kidney problems, such as kidney failure or frequent urination
• Recurrent infections
• Unexplained weight loss

An abnormal result from the Immunofixation Quantitative Urine test can indicate a number of different conditions, including multiple myeloma, Waldenstrom's macroglobulinemia, and other plasma cell disorders.

You will be asked to provide a urine sample. The sample will be collected in a sterile container and sent to the laboratory for analysis.

No special preparation is required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

In addition to Immunofixation Quantitative Urine test, other laboratory tests that may be ordered to evaluate plasma cell disorders include:

• Serum protein electrophoresis (SPEP): This test measures the levels of various types of proteins in the blood, including M proteins.
• Free light chain assay: Abnormal levels of free light chains can be indicative of plasma cell disorders.
• Complete blood count (CBC): This test evaluates the number and types of blood cells present in the blood.
• Renal function tests: These tests evaluate how well the kidneys are functioning and can help detect any damage caused by abnormal proteins.
• Beta-2 microglobulin: This test measures the levels of a protein that is often elevated in plasma cell disorders.
• Bone marrow biopsy: This test involves taking a small sample of bone marrow and evaluating it for the presence of abnormal cells.

• Immunofixation Electrophoresis (IFE) Urine Test
• Urine Protein Electrophoresis (UPEP) Test
• Serum Protein Electrophoresis (SPEP) Urine Test
• Urine Immunoelectrophoresis Test (UIEP)
• Urine Monoclonal Gammopathy Test
• Urine M-Spike Test