IgG Subclass 1 (IgG1) Serum Test by Nephelometry

The IgG1 serum test measures the levels of IgG1 in your blood.

• To evaluate patients with signs and symptoms of humoral immunodeficiency or combined immunodeficiency
• To assess chronic active infection or inflammation
• To aid in the diagnosis and monitoring of plasma cell disorders
• To determine the effectiveness of treatment for immune-related conditions

This test may be recommended if you have

• clinical signs and symptoms suggesting immunodeficiency or combined immunodeficiency,
• chronic active infections or inflammation,
• suspected plasma cell disorders, or
• previously diagnosed immune-related conditions that require monitoring.

Abnormal levels may indicate immune deficiencies, chronic infections, inflammation, or plasma cell disorders.

A small blood sample will be collected from your arm. The sample will be sent to the laboratory for analysis.

• Follow any dietary restrictions or fasting instructions given by your doctor, if any.
• Inform your doctor about any medications you are currently taking, as certain drugs can affect the test results. Also, tell them if you have any specific requirements.

• Total IgG Level: Measures the total amount of immunoglobulin G in the blood.
• Additional IgG Subclass Tests: Measures other subclasses of immunoglobulin G.

Serum IgG1 Test or Nephelometric Assay for IgG Subclass 1

Humoral immunodeficiency or combined immunodeficiency refers to conditions where the body's immune system, particularly the antibody-mediated response, is compromised. This can result in increased susceptibility to infections.