HCV Genotyping by PCR & Sanger Sequencing (Serum or Plasma)

This test measures the specific genotype of the Hepatitis C Virus (HCV) in your blood. Genotyping helps determine the strain of the virus and guides treatment decisions to ensure optimal results.

• To guide treatment decisions: Different HCV genotypes respond differently to antiviral drugs, so knowing your genotype helps choose the most effective treatment.
• Assess disease progression: Certain HCV genotypes are associated with a higher risk of liver damage and disease progression.
• Determine transmission sources: Identifying the genotype can help trace the source of infection in certain cases.

This test is recommended for individuals with:

• Chronic Hepatitis C infection to determine the specific genotype and guide treatment decisions
• Previous or current treatment failure, as a change in therapy might be required
• Before initiating therapy, to select appropriate antiviral drugs
• Recipients of blood transfusions or organ transplants to identify the source of infection

The result will indicate the specific genotype of the Hepatitis C Virus in your blood. Abnormal results may suggest a high-risk genotype associated with more severe liver damage or indicate resistance to certain antiviral drugs. Discuss the results with your doctor for further evaluation and appropriate treatment recommendations.

• A small blood sample will be collected from your vein.
• PCR (Polymerase Chain Reaction) and Sanger sequencing techniques will be used to identify your Hepatitis C genotype.
• The laboratory will analyse the genetic material of the virus to determine its genotype.
• You will receive the test results from your healthcare provider.

Reach out to your healthcare provider for any specific requirements.

Other tests that may be ordered alongside HCV Genotyping include:

• HCV Viral Load Testing: Measures the amount of Hepatitis C Virus RNA in the blood to determine the severity of infection.
• Liver Function Tests: Assess liver health and determine if hepatitis C has caused any liver damage.
• HCV Antibody Testing: Confirms whether you have been exposed to the Hepatitis C Virus.

Hepatitis C Virus Genotyping using Polymerase Chain Reaction (PCR) and Sanger Sequencing

Hepatitis C is a viral infection that primarily affects the liver. It can lead to chronic liver disease if left untreated. The virus is transmitted through contact with infected blood.