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HBV Mutation Profile by PCR & Sanger Sequencing - Serum

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Overview

The HBV Mutation Profile by PCR and Sanger Sequencing is a comprehensive diagnostic test used to identify drug-resistant mutations in the hepatitis B virus (HBV). This test utilizes polymerase chain reaction (PCR) amplification followed by Sanger sequencing to analyze specific regions of the HBV genome associated with drug resistance.

By analyzing the HBV mutation profile, this test provides valuable information about the presence of mutations that can confer resistance to antiviral drugs commonly used in the treatment of chronic hepatitis B. It can identify specific genetic changes in the HBV DNA polymerase gene, which is the target of many antiviral medications.

The HBV Mutation Profile by PCR and Sanger Sequencing can detect a wide range of mutations associated with drug resistance, including those related to lamivudine, adefovir, entecavir, tenofovir, and other antiviral drugs.

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HBV Mutation Profile by PCR & Sanger Sequencing - Serum Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the HBV Mutation Profile by PCR & Sanger Sequencing - Serum with a clear pricing structure.

The HBV Mutation Profile by PCR & Sanger Sequencing - Serum Price in Mumbai is ₹ 11,550 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

This test measures the presence of drug-resistant mutations in the Hepatitis B Virus (HBV).

  • To identify drug-resistant HBV mutations in people with chronic hepatitis B
  • To evaluate treatment response in people with hepatitis B undergoing antiviral therapy

Your doctor might recommend this test if you have

  • chronic Hepatitis B,
  • symptoms of liver disease like jaundice, fatigue, and abdominal pain,
  • history of Hepatitis B infection, or
  • been exposed to someone with Hepatitis B virus.

An abnormal result indicates that there are some mutations present in the virus, which can make treatment difficult.

A small sample of blood will be taken from your arm. The blood sample will undergo PCR & Sanger Sequencing to identify any mutations present in HBV.

  • Inform your doctor about all medications you are currently taking and any specific requirements you have.
  • Drink plenty of water and eat before the test.
  • Liver function tests to assess liver health of the patient
  • HBV DNA quantification to measure the amount of virus in the blood

HBV drug resistance refers to the ability of the hepatitis B virus (HBV) to develop genetic mutations that reduce or eliminate the effectiveness of antiviral medications used in the treatment of chronic hepatitis B. These mutations occur in specific regions of the HBV genome, particularly within the HBV DNA polymerase gene, which is the target of many antiviral drugs. Antiviral medications are commonly prescribed to suppress HBV replication, reduce liver inflammation, and prevent the progression of liver disease.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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