G6PD Quantitative Reflex Qualitative Test

To check for the presence of inherited G6PD deficiency.

Your doctor may recommend a G6PD quantitative blood test if he suspects you may have haemolytic anemia based on symptoms such as:

• An enlarged spleen
• Weakness
• Dizziness
• Jaundice
• Pale skin
• Increased heart rate
• Darker coloured urine
• Breathlessness

Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme involved in energy production. It is present in all the cell, including red blood cells and helps protect them from certain toxic by-products of cellular metabolism. A deficiency in G6PD causes RBCS to become susceptible to haemolysis (breakage). G6pd quantitative blood test test measures the G6PD levels in RBCs to help identify the deficiency.

• G6PD Quantitative Reflex Qualitative test is done to diagnose G6PD deficiency.
• It is done to determine the severity of G6PD deficiency.
• It also helps to monitor the response to treatment.

The G6PD Quantitative Reflex Qualitative test measures the activity of the G6PD enzyme.

An abnormal result of this test indicates that the level of G6PD in the blood is lower than normal. This could be due to a genetic mutation, medications, or other factors

The test involves drawing a small amount of blood from a vein in your arm. A healthcare professional will clean the area with an antiseptic, wrap an elastic band around your upper arm to make the veins more visible, and insert a needle into a vein to collect the blood sample. You may feel a brief prick or stinging sensation when the needle is inserted, but the procedure is generally painless.

No special preparation is required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

The following symptoms may indicate the need for a G6PD Quantitative Reflex Qualitative test:

• Jaundice (yellowing of the skin and eyes)
• Dark urine
• Fatigue
• Rapid heart rate
• Shortness of breath
• Pale skin
• Enlarged spleen

If a G6PD Quantitative Reflex Qualitative test indicates that a person has G6PD deficiency, additional tests may be ordered to determine the severity of the deficiency and to rule out other underlying conditions. These tests may include:

• Complete Blood Count (CBC): A CBC measures the number of red blood cells, white blood cells, and platelets in the blood. It can help determine if the person has anemia or other blood disorders.
• Reticulocyte Count: This test measures the number of immature red blood cells in the blood. It can help determine if the bone marrow is producing enough red blood cells to replace the ones that are being destroyed.
• Bilirubin Test: Bilirubin is a waste product that is produced when red blood cells break down. High levels of bilirubin in the blood can cause jaundice, which is a common symptom of G6PD deficiency.
• Hemoglobin Electrophoresis: This test can determine if a person has any abnormal forms of hemoglobin, which can cause anemia and other blood disorders.
• Enzyme Activity Assay: This test measures the activity of the G6PD enzyme in the blood. It can help determine the severity of the deficiency.
• Genetic Testing: Genetic testing can determine if a person has inherited G6PD deficiency and which type of deficiency they have.

Glucose-6-Phosphate Dehydrogenase Test

Quantitative G6PD Test

Qualitative G6PD Test