FSH LH TSH Prolactin Profile Test

FSH-LH-Prolactin-TSH test is done to diagnose fertility issues in males and females. In women, the reason depends on at what age and stage it is done. It may be done to diagnose menstrual irregularities, or any dysfunctions . In women having difficulties conceiving, it is done to diagnose the cause for infertility. It may also be done to diagnose any thyroid disorders which may affect the reproductive health. It is done in males to diagnose reasons for infertility, low sperm count, testicular issues or any thyroid disorders. In children it may be done to diagnose early or delayed puberty based on the levels.

This test is used to check for fertility issues among women as well as men. If facing irregularities in menstrual cycles, this test can help find out the reasons behind it. In women of reproductive age, this test is used to evaluate the reasons behind infertility.

In males, it is chiefly done to check for infertility, reduced sperm count, testicular issues or thyroid disorders. In children, these tests are used to diagnose delayed or early puberty.

If you have the following issues, your doctor will recommend this test:

• Difficulty conceiving
• Infertility in men and women
• Low sperm count
• Irregular periods/PCOS/PCOD
• Sudden weight gain
• Early puberty
• Late puberty
• Difficulty in lactation after delivery
• Slow or high metabolism

FSH lh tsh prolactin test measures the levels of FSH, LH, Prolactin and Testosterone hormones in the blood.

During fsh lh tsh prolactin test blood sample is taken from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a  little sting when the needle goes in or out. This usually takes less than five minutes. In new-borns the blood is taken from the skin behind the heel.

FSH-LH-Prolactin-TSH levels are important for successful conception. Abnormal levels in any of these may lead infertility issues. 
High FSH-LH-Prolactin-TSH levels in women may mean primary ovarian insufficiency or polycystic ovarian syndrome (PCOS), ovarian and uterine malignancies. High TSH may cause hyperthyroidism affecting the sexual function and reproduction. In men, high FSH-LH-Prolactin-TSH  may indicate testicular issues, sexual dysfunctions or low sperm count. All these may indicate infertility in men. In children, high levels before puberty, signify early onset puberty. 
Low levels may lead to lack of ovulation and sperm production leading to infertility issues in both men and women. Low levels may be due to problems in the hypothalamus or pituitary gland, being underweight or other central nervous system issues. Low TSH levels lead to hypothyroidism in males and females.

Wear loose-fitting clothes. Ask the doctor about any doubts one may have. Drink only water for 8-12 hours before the test. The FSH and LH are best taken on the 2nd or 3rd day of the menstrual cycle.

The reference range for FSH is as follows:

Females:

Follicular phase: 3.1-7.9 mIU/mL

Ovulation peak: 2.3-18.5 mIU/mL

Luteal phase: 1.4-5.5 mIU/mL

Postmenopausal: 30.6-106.3 mIU/mL

Males:

Age 0-7 years: <6.7 mIU/mL

Age 8 years-adult:1.3-19.3 mIU/mL

The following values are considered to be normal LH blood levels:

Women:

Follicular phase of the menstrual cycle: 1.9 to 12.5 IU/L

LH surge: 8.7 to 76.3 IU/L

Luteal phase of the menstrual cycle: 0.5 to 16.9 IU/L

Pregnancy: less than 1.5 IU/L

Post-menopause: 15.9 to 54.0 IU/L

Women using contraceptives: 0.7 to 5.6 IU/L

Men:

Age group of 20 and 70 years: 0.7 to 7.9 IU/L

>70 years of age: 3.1 to 34.0 IU/L

The following values are considered to be normal prolactin blood levels:

Males > 18 years: 2.10 - 17.70 ng/mL

Adult Females

Non-pregnant: 2.80 - 29.20 ng/mL

Pregnant: 9.70 - 208.50 ng/mL

Post Menopausal: 1.80 - 20.30 ng/mL

The normal values for TSH are as follows:

Men and Women:

>/= 20 years: 0.40 - 4.50 mIU/L

Pregnant Women:

First Trimester: 0.26-2.66 mIU/L

Second Trimester: 0.55-2.73 mIU/L

Third Trimester: 0.43-2.91 mIU/L

Some of the tests that are ordered along with the FSH-LH-Prolactin-TSH test:

• Complete Blood Count (CBC)
• Anti-Mullerian Hormone (AMH) test
• Insulin (fasting) test
• Hb1Ac, Glycated Hemoglobin test

References:

1. Wheeler M. J. (2013). The measurement of LH, FSH, and prolactin. Methods in molecular biology (Clifton, N.J.), 1065, 105–116. https://doi.org/10.1007/978-1-62703-616-0_6
2. https://www.1mg.com/labs/test/fsh-lh-prolactin-tsh-2375

• ·       Hormone Profile
• Fertility Profile
• ·       Follicle Stimulating Hormone (FSH)
• ·       Luteinising Hormone (LH)
• ·       Prolactin (PRL)
• Thyroid Stimulating Hormone (TSH)