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Complement Total Serum CH50 Test in Dadar

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CH50 Test Overview

The CH50 test is a laboratory test that measures the total complement activity in serum. A complement is a group of proteins that forms part of the innate immune system. The CH50 test is used to help diagnose and monitor certain autoimmune and inflammatory diseases and is prescribed to assess the effectiveness of the complement system in the body. 

Harmful pathogens that invade the body are eliminated by the immune system with the aid of this mechanism. Several proteins that make up the complement system are secreted by the liver and can be in such abundance that they can account for up to 5% of the globulin fraction in a blood sample.

The complement system is made of proteins which are a part of the immune system. There are close to 30 proteins that work together to protect the body against any infections or diseases. The main function of these proteins is to form antibodies against infections, destroy dead cells, neutralize the virus and bacteria, and build immunity. But at times they may even destroy healthy tissues leading to autoimmune disorders. CH50 serum test is a blood test that detects the overall activity of these proteins, especially the complement activation pathway.

People with the following conditions should go for this test:

  • Have butterfly-shaped rashes on their skin
  • Suffering from fatigue, mouth sores, and hair loss
  • Show sensitivity to sunlight
  • Have pain in the joints
  • Have chronic fever and heart pain while breathing
  • Have lymph nodes that are swollen

Written by: Dr. Shibani R, Medical Writer, Medical Affairs







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Complement Total Serum CH50 Test Price in Dadar

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Complement Total Serum CH50 Test with a clear pricing structure

The price of Complement Total Serum CH50 Test in Dadar is ₹ 4,890

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The test is recommended when a person is suffering from any infections, inflammation of unknown origin, autoimmune disorders, is taking treatment for any such immunological disorders. The complement can serve as measure of the immune system activity. In case of persistent microbial infections, the test can give information about the immune system dysfunction-based on low levels of complement. In case of autoimmune disorder, low levels are present as the body consumes the complement without any substantial purpose.

Your doctor would recommend this test for you if you have the following conditions:

  1. Rheumatoid Arthritis 
  2. Kidney Disease
  3. Bacterial Meningitis
  4. Hemolytic uremic syndrome (HUS)

The complement system helps or “complements” augmenting the ability of phagocytes or antibodies to help fight against infections and agents that the body classifies as foreign, “antigen”. It belongs to the immune system and comprises of proteins that are produced in the liver.

However, when the body attacks these “antigens” it creates harm to it’s own tissues, and hence the concentration of this complement should be tightly controlled.  Thus, the proteins which control the level of this complement are always present in a higher amount than the proteins themselves.

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