Clustered AchR, MuSK and LRP4 Antibodies

Also known as: Clustered AchR, MuSK, LRP4 Antibodies, Serum**

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Male, Female

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Overview

The analysis of clustered Acetylcholine Receptor (AChR), Muscle-Specific Kinase (MuSK), and Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) antibodies serves a vital role in diagnosing patients with Myasthenia Gravis (MG). MG is an autoimmune neuromuscular disorder characterized by muscle weakness and fatigue due to the impairment of neuromuscular transmission. Detection of antibodies against AChR, MuSK, and LRP4 helps differentiate between different subtypes of MG. AChR antibodies are found in the majority of MG patients, while MuSK antibodies are associated with a distinct form of the disease that often affects facial and bulbar muscles. LRP4 antibodies have also been linked to a subset of MuSK-negative MG patients. Testing for these antibodies aids clinicians in accurately diagnosing MG subtypes and tailoring appropriate treatments, enhancing patient management and outcomes.

Clustered AchR, MuSK, LRP4 Antibodies, Serum** Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Clustered AchR, MuSK, LRP4 Antibodies, Serum** with a clear pricing structure.

The Clustered AchR, MuSK, LRP4 Antibodies, Serum** Price in Mumbai is ₹ 16,050 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

What does the Clustered AchR and MuSK and LRP4 Antibodies test measure?

This test measures the presence of antibodies in your blood that target the Clustered Acetylcholine Receptor (AchR), Muscle-Specific Kinase (MuSK), and Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4).

Why is the Clustered AchR and MuSK and LRP4 Antibodies test done?

• To diagnose patients with Myasthenia Gravis • To differentiate between different subtypes of MG, such as AchR antibody-positive MG, MuSK antibody-positive MG, or LRP4 antibody-positive MG • To monitor the response to treatment and evaluating disease progression

When is the Clustered AchR and MuSK and LRP4 Antibodies test recommended and who should take the test?

• Your doctor might recommend this test if you have symptoms such as muscle weakness, difficulty swallowing or breathing, drooping eyelids, or double vision. • The test may also be recommended if you have a family history of MG or if your doctor suspects you may have an autoimmune disorder affecting the neuromuscular junction.

What if the results of the Clustered AchR and MuSK and LRP4 Antibodies test are abnormal?

The presence of antibodies targeting AchR, MuSK, or LRP4 in your blood indicates a high likelihood of Myasthenia Gravis. • Presence of AchR antibodies: Suggestive of AchR antibody-positive MG • Presence of MuSK antibodies: Suggestive of MuSK antibody-positive MG • Presence of LRP4 antibodies: Suggestive of LRP4 antibody-positive MG

What to expect during the Clustered AchR and MuSK and LRP4 Antibodies test?

During this test, a healthcare professional will draw a small sample of blood from your vein. The blood sample will be sent to the laboratory for analysis using a cell-based assay method.

What preparations are required before the Clustered AchR and MuSK and LRP4 Antibodies test?

Inform your doctor about any medications or supplements you are currently taking, as some medications may interfere with the accuracy of the test results. Also, let them know if you have any specific requirements.

What other tests may be ordered with Clustered AchR and MuSK and LRP4 Antibodies test?

• Electromyography (EMG): This test measures the electrical activity in your muscles and helps evaluate the neuromuscular function. • Nerve Conduction Studies (NCS): This test measures how well your nerves are conducting electrical signals to the muscles.

What is the Clustered AchR and MuSK and LRP4 Antibodies test also known as?

Clustered Acetylcholine Receptor (AchR), Muscle-Specific Kinase (MuSK), and Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) Antibodies test

What is Myasthenia Gravis?

Myasthenia Gravis (MG) is a chronic autoimmune disorder that affects the neuromuscular junction, causing muscle weakness and fatigue. It occurs when the immune system mistakenly produces antibodies that target and interfere with the normal functioning of AchR, MuSK, or LRP4 receptors at the neuromuscular junction. MG can affect any voluntary muscle in the body, including those involved in breathing and swallowing.

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