Clostridium Difficile GDH Reflex Toxin A/B**

This test measures the presence of Clostridium difficile antigen GDH in the stool sample. It also detects the toxins A and B produced by this bacterium if GDH test turns positive. These measurements help in diagnosing Clostridium difficile infection, a common cause of diarrhea and other gastrointestinal symptoms

• The test is essential for diagnosing Clostridium difficile infection.
• It identifies the presence of the bacterium and its toxins in stool samples.
• Results guide proper treatment, preventing infection spread.
• The test aids in monitoring treatment effectiveness.

The test is recommended if you:

• Exhibit symptoms of gastrointestinal infection like severe diarrhea or abdominal pain
• Have recently been hospitalised or undergone antibiotic treatment.
• Are at risk of Clostridium difficile infection.

Are facing recurrent episodes of the infection

In a normal stool sample, the Clostridium difficile antigen GDH is not detected, and toxins A and B are absent. If the test shows the presence of GDH or toxins A and B, it may indicate a Clostridium difficile infection. However, abnormal results do not necessarily mean that you have an active infection.

• Abnormal results may require further testing or evaluation by your doctor
• Your doctor will interpret the results in the context of your clinical history and other tests
• Treatment decisions should not be based solely on the results of this test

• You will be provided with a sterile, leak-proof container to collect a 5gm stool sample.
• Ensure proper collection technique and follow any instructions provided by your healthcare provider.
• The sample should be submitted to the laboratory for testing within 72 hours of collection.

Before the test:

• Inform your doctor of any recent antibiotic use or hospitalisation.
• Follow any dietary restrictions or instructions given by your doctor or healthcare provider.
• Avoid using enemas or laxatives before providing the stool sample.

Other tests that may be ordered alongside this test include:

• Complete Blood Count (CBC): to check for signs of infection and evaluate white blood cell count
• Stool Culture: to identify other bacteria causing gastrointestinal symptoms
• Polymerase Chain Reaction (PCR): for additional confirmation of Clostridium difficile infection

Clostridium difficile antigen GDH and toxin A/B detection by CLIA

Clostridium difficile infection is a common bacterial infection of the gastrointestinal tract. It causes symptoms such as diarrhea, abdominal pain, and fever. The infection is often associated with antibiotic use, healthcare settings, and prolonged hospital stays. Prompt diagnosis and treatment are important to prevent complications and spread of infection.