Prenatal Chromosomal Array CGH Test in T Nagar
50+ booked in last 3 daysTest Overview
Chromosomal Array, Comparative genomic hybridization (CGH) is a confirmatory & an invasive test which is done prenatally to identify foetal anomalies i.e., chromosomal aneuploidy, other large structural changes, sub microscopic abnormalities that are not detected by karyotyping. CGH Chromosome Array Test requires detailed clinical history including anomaly scan report and a duly filled consent form (Form G)
Array CGH Prenatal helps in the detection of copy number variations (CNV) changes (microdeletions and microduplications).
Conventional karyotyping is used to detect chromosomal problems in about 35% of pregnancies. However, its accuracy depends on the quantity and type of fetal ultrasonography anomalies present. Prenatal karyotyping is a reliable procedure that can identify the majority of germline chromosomal abnormalities. Most of these anomalies are associated with the phenotype. For postnatal diagnosis of people with congenital defects and intellectual incapacity, array-comparative genomic hybridization (CGH)/(single nucleotide polymorphism is very common. It has a high probability of accurate abnormality detection and is automation-friendly. This makes it the perfect choice for a prenatal diagnosis.
To discover fetal defects such as chromosomal aneuploidy, other significant structural changes, and submicroscopic abnormalities that are not picked up by karyotyping, a confirming and invasive test called CGH is performed during pregnancy. A complete consent form and a clinical history that includes the anomaly scan report are required for the test (Form G).
CGH has been established to aid in prenatal diagnosis. It is used to examine structural chromosomal rearrangements linked to copy number variations on a genome-wide scale. Test and standard genomic DNAs are fluorescently labeled with two separate fluorochromes and hybridized to healthy metaphase chromosomes in CGH. Genome-wide copy number alterations, such as homo- or heterozygous deletions, gains, or amplifications, can be detected by determining the relative genomic copy number throughout each chromosome.
Written by: Dr Vishal Wadhwa M.D, D.N.B Microbiology, Medical Affairs
Prenatal Chromosomal Array CGH Test Price in Chennai
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Prenatal Chromosomal Array CGH Test with a clear pricing structure
The price of Prenatal Chromosomal Array CGH Test in Chennai is ₹ 16,960
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
To determine the risk for the fetus being born with certain Genetic (chromosomal) abnormalities.
This test is for pregnant women to determine the risk for the fetus being born with certain Genetic (chromosomal) abnormalities.
This test is for detection of Copy number variations changes (microdeletions and microduplications). Detailed clinical history including anomaly scan report must be submitted with sample. Duly signed consent form as per PCPNDT must.
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