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Anti GAD-65 Paraneoplastic Syndrome Serum in Indiranagar
52+ booked in last 3 days
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
Test Overview
Glutamic acid decarboxylase (GAD65) is an enzyme that is produced primarily by pancreatic islet cells. Patients with insulin-dependent diabetes mellitus (IDDM) often have antibodies to GAD65 and several other islet cell antigens.
The GAD65 antibody is a biomarker of autoimmune central nervous system (CNS) disorders and, more commonly, non-neurological autoimmune diseases, like Type 1 diabetes, autoimmune thyroid disease, and pernicious anemia.
Anti-GAD-65 paraneoplastic syndrome is a rare neurological disorder caused by the immune system attacking the body's nervous system, specifically the GAD-65 protein. The GAD-65 protein is an enzyme that is involved in the production of a neurotransmitter called gamma-aminobutyric acid (GABA), which helps to regulate the communication between nerve cells in the brain and spinal cord.
In the case of anti-GAD-65 paraneoplastic syndrome, the immune system produces antibodies against the GAD-65 protein, leading to a reduction in GABA production and disrupting nerve cell communication.
The paraneoplastic aspect of this syndrome means that it is associated with certain types of cancer, typically small-cell lung cancer, breast cancer, or ovarian cancer. In some cases, anti-GAD-65 antibodies are produced as part of the body's immune response to the cancer, rather than as a direct result of the cancer itself.
Associated Tests:
Yo Antibody Neuronal antibody for Paraneoplastic syndromes Serum
Amphiphysin Antibody Neuronal Ag in Paraneoplastic Syndrome Serum
Hu Antibody Neuronal ag in Paraneoplastic syndromes Serum
Ri Antibody, Serum
PNMA2 (MA2/TA) Antibody Serum
Neuronal Antibody Profile
Neuronal Antibody Profile-3
Written by : Supriya Kulkarni, Lead-Content & Training
Anti GAD-65 Paraneoplastic Syndrome Serum Price in Bangalore
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Anti GAD-65 Paraneoplastic Syndrome Serum with a clear pricing structure
The price of Anti GAD-65 Paraneoplastic Syndrome Serum in Bangalore is ₹ 7,085
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
GAD-65 antibody is useful to diagnose Insulin dependent Diabetes mellitus (IDDM) and development of related endocrine disorders like Thyroiditis. It is also used to diagnose Stiff Man syndrome & automimmune encephalitis.
This test is performed for patients suspected of suffering from autoimmune diseases like Insulin Dependent Diabetes Mellitus, Stiff Man syndrome & autoimmune encephalitis.
Glutamic acid decarboxylase (GAD65) is an enzyme that is produced primarily by pancreatic islet cells. Patients with insulin-dependent diabetes mellitus (IDDM) often have antibodies to GAD65 and several other islet cell antigens. Also High serum levels of antibodies to the synaptic enzyme glutamic acid decarboxylase (GAD-abs) is a very sensitive biomarker of stiff-person syndrome (SPS) and have also been described in subgroups of patients with limbic encephalitis (LE), cerebellar ataxia,epilepsy, and isolated cases of palatal tremor, as well as downbeat or periodic alternating nystagmus. Patients with GAD-abs must be screened for an underlying cancer if they have clinical presentations different from those typically associated with this autoimmunity or develop classic PNS.
How it Works?
All our phlebotomists are vaccinated
At Metropolis Healthcare, your well-being is our top priority. Rest assured, all our skilled phlebotomists are vaccinated, ensuring a safe and secure experience for you. Our team upholds the highest healthcare standards, and your health is in capable hands. Your safety is non-negotiable, and at Metropolis, we take every measure to guarantee it.
Our Phlebotomists maintain a high standard of safety precautions
Our dedicated team of phlebotomists prioritises your safety before anything else. They implement stringent safety measures to guarantee your well-being during their visit.
Strictly adhering to aseptic techniques, our phlebotomists maintain a sterile environment with thorough sanitization and the use of gloves, masks and face shields. Needles are disposed of with utmost care, following rigorous guidelines to minimise any potential risks. We leave no room for compromise when it comes to personal protective equipment (PPE), ensuring both you and our staff are well protected.
Our phlebotomists collect samples safely
The phlebotomists at Metropolis Healthcare are proficient in safe sample collection. They skillfully and gently draw blood, minimizing any discomfort you may feel. We prioritize your safety by using sterile, single-use needles and barcoded vials to completely eliminate any risk of cross-contamination. Our collection area is carefully sanitized before, during, and after your sample collection.
Samples are processed at high-tech facilities
Metropolis Healthcare takes pride in its state-of-the-art facilities, where your samples are thoroughly processed. Our labs are equipped with cutting-edge machinery with advanced technology, eliminating chances of human error. From the moment your sample arrives at our facility, it undergoes an automated process.
Your samples are stored in clean and secure facilities
We leave no room for compromise when it comes to the storage of your samples. Our storage facilities are regularly cleaned and disinfected, upholding the highest standards of healthcare safety.
Temperature-controlled environments and cooling facilities ensure that your samples remain fresh and the results produced are accurate. Our cutting-edge security measures prevent unauthorized access, guaranteeing the confidentiality of your health data.
Metropolis provides accurate digital reports
Our advanced sample processing machines not only deliver swift results to you but also generate precise digital reports. We provide conclusive diagnoses through meticulous re-checks and repeat specimen analyses, if required, at no extra cost, adding an extra layer of accuracy and dependability. This unique approach sets us apart, earning the trust of top doctors and hospitals across the country.
Your health is our priority, and we spare no effort in our commitment to providing you with the most accurate insights you can rely on.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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