Home Visit
Upload
.png)
HLA B27 Test (Human Leucocyte Antigen B27) in Bandra
55+ booked in last 3 days
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 48 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
HLA B27 Test Overview in Bandra
Human leukocyte antigen HLA-B27 is a MHC (major histocompatibility complex) class I surface antigen encoded by the B locus on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammatory bowel disease, and reactive arthritis. HLA B27 is considered to be an important criterion for the classification of axial spondyloarthropathies & helps in establishing early diagnosis of ankylosing spondyloarthropathies before the development of irreversible deformities. HLA-B27 is present in approximately 89% of patients with ankylosing spondylitis, 79% of patients with Reiter syndrome, and 42% of patients with juvenile rheumatoid arthritis. However, it is not diagnostic for these disorders. Approximately 8% of the normal population carries the HLA-B27 antigen.
The HLA B27 test, also known as the human leukocyte antigen B27 test, is a blood test designed to detect the presence of the HLA-B27 antigen on the surface of white blood cells (WBCs). This antigen is a protein involved in the immune system, helping it identify and distinguish between the body's own cells and foreign substances.
The HLA B27 test is crucial for assessing the risk of developing certain autoimmune diseases, particularly those affecting the joints and spine, such as ankylosing spondylitis, reactive arthritis, and juvenile rheumatoid arthritis.
The HLA B27 blood test in Bandra is an essential diagnostic tool for individuals experiencing symptoms such as chronic back pain, neck stiffness, joint inflammation, and eye inflammation. It is also recommended for those with a family history of autoimmune disorders associated with HLA-B27. Additionally, the human leukocyte antigen b27 test plays a vital role in ensuring compatibility between donors and recipients during kidney and bone marrow transplants, as well as evaluating the progression and management of diseases linked to the HLA-B27 antigen.
Reasons for Undergoing the HLA B27 Test in Bandra
A doctor may recommend an HLA B27 test in Bandra for several critical reasons:
- Diagnosis of Autoimmune Disorders: The human leukocyte antigen b27 test helps identify autoimmune diseases like ankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis, and other spondyloarthritis types, enabling timely diagnosis and treatment.
- Symptom Evaluation: Individuals experiencing chronic back pain, neck stiffness, joint inflammation, or eye inflammation may undergo the human leukocyte antigen b27 test to confirm or rule out conditions linked to the HLA-B27 antigen.
- Family History of Autoimmune Disorders: Those with a family history of autoimmune diseases associated with human leukocyte antigen b27 are often tested to assess their risk of developing similar conditions.
- Transplant Compatibility: In kidney or bone marrow transplants, the HLA B27 test ensures donor-recipient compatibility, reducing the risk of rejection.
- Disease Management: For patients already diagnosed, this test aids in monitoring the progression and management of autoimmune diseases linked to HLA-B27, ensuring personalised and effective care.
List of Parameters Considered During the HLA B27 Test in Bandra
The HLA B27 blood test measures the presence or absence of the human leukocyte antigen b27 on the surface of white blood cells. The key parameters include:
- Presence of HLA-B27 Antigen: Indicates that the individual carries the human leukocyte antigen b27 gene variant, which is associated with an increased risk of developing certain autoimmune diseases.
- HLA-B27 Positive: Shows that the antigen is present, suggesting a higher risk for conditions like ankylosing spondylitis.
- HLA-B27 Negative: Indicates that the antigen is not present, which does not rule out the possibility of having an autoimmune disorder but suggests a lower risk.
- HLA-B27 Moderate: Sometimes referred to as a "grey zone," this indicates levels close to the cutoff and may require further testing.
HLA B27 Test Preparation
Preparing for the HLA B27 test is relatively straightforward, as there is no need for fasting. Consult your doctor before taking any over-the-counter medications.
HLA B27 Test Results & Interpretation
The results of the HLA B27 test are reported as:
- Positive: Indicates the presence of the human leukocyte antigen b27, suggesting a higher risk for associated autoimmune diseases.
- Negative: Indicates the absence of the HLA-B27 antigen, which does not confirm or rule out autoimmune diseases but suggests a lower risk.
- Moderate (Grey Zone): Levels close to the cutoff; further testing may be necessary.
Interpretation should be done in conjunction with clinical symptoms, medical history, and other diagnostic tests. A positive result alone does not confirm a diagnosis but is a predisposing factor for certain autoimmune conditions.
Home Collection for HLA B27 Test in Bandra Near You
Metropolis Healthcare offers a convenient home sample collection service for the HLA B27 test in Bandra, ensuring that you can get tested without the need to visit a laboratory. A trained phlebotomist will come to your doorstep to collect the blood sample, maintaining the highest standards of safety, hygiene, and sample handling. This service ensures that you can undergo the test in the comfort of your home without compromising on the accuracy of the results.
With Metropolis Healthcare's commitment to making healthcare accessible and providing quality diagnostic solutions, you can expect timely and reliable results, empowering you to take proactive steps in managing your health.
HLA B27 Test (Human Leucocyte Antigen B27) Price in Bandra
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the HLA B27 Test (Human Leucocyte Antigen B27) with a clear pricing structure
The price of HLA B27 Test (Human Leucocyte Antigen B27) in Bandra is ₹ 2,500.
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The HLA B27 test, also known as the human leukocyte antigen B27 test, is a blood test that detects the presence of the HLA-B27 antigen in white blood cells. It helps assess the risk of developing certain autoimmune diseases affecting the joints and spine.
To book an HLA B27 test in Bandra, you can either visit a local diagnostic centre or book online through various healthcare platforms. Many laboratories, like Metropolis Healthcare, offer online booking options, allowing you to schedule an appointment at your convenience.
Yes, many diagnostic centres in Bandra offer home sample collection services for the HLA B27 blood test. This means a trained phlebotomist will visit your home to collect the blood sample, making the process more convenient for you.
The normal range for the human leukocyte antigen B27 test is reported as either positive or negative. A negative result indicates the absence of the HLA-B27 antigen, while a positive result suggests its presence. The presence of the antigen is associated with an increased risk of certain autoimmune diseases.
High levels of HLA B27, or a positive result, indicate the presence of the HLA-B27 antigen on white blood cells. This suggests an increased risk of developing autoimmune diseases such as ankylosing spondylitis, reactive arthritis, and juvenile rheumatoid arthritis.
The human leukocyte antigen B27 test is used to diagnose and manage autoimmune diseases, particularly those affecting the joints and spine. It helps assess the risk of conditions like ankylosing spondylitis and reactive arthritis and is also used to ensure compatibility in organ transplants.
The frequency of human leukocyte antigen B27 testing depends on your individual health needs and your doctor's recommendations. It is not a routine test and is typically recommended based on symptoms or a family history of autoimmune disorders.
The presence of human leukocyte antigen B27 is associated with an increased risk of developing autoimmune diseases such as ankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis, and other inflammatory conditions affecting the joints, spine, and eyes.
The HLA B27 test can be done at any time, as it does not require fasting or specific timing.
No, fasting is not required for the HLA B27 test.
Before getting the HLA B27 test, inform your doctor about any medications you are taking and any existing health conditions.
The HLA B27 test specifically measures the presence or absence of the HLA-B27 antigen on the surface of white blood cells. It does not include any other parameters.
The HLA B27 test involves a standard blood draw from a vein in your arm. The collected blood sample is then sent to a laboratory for analysis using techniques such as flow cytometry or polymerase chain reaction (PCR).
The HLA B27 test should be done if you have symptoms suggestive of autoimmune diseases, a family history of such conditions, or as recommended by your healthcare provider during medical evaluations. It is particularly relevant for individuals with chronic back pain, joint inflammation, or eye inflammation.
A negative HLA B27 blood test result means that the HLA-B27 antigen is not present in your white blood cells. While this lowers the likelihood of developing certain autoimmune diseases, it does not completely rule out the possibility of having these conditions.
HLA-B27 is associated with several autoimmune diseases, including ankylosing spondylitis, reactive arthritis, psoriatic arthritis, juvenile idiopathic arthritis, and anterior uveitis. The presence of the antigen increases the risk of developing these conditions.
The prevalence of human leukocyte antigen B27 varies among different populations. While it is more common in certain ethnic groups, such as Caucasians, it is relatively rare in the general population. Approximately 6-8% of Caucasians are HLA-B27 positive.
Additional tests that may be recommended along with the HLA B27 test include erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), and imaging tests like X-rays or MRI scans to assess joint and spine health.
The blood sample collection for the human leukocyte antigen B27 test usually takes only a few minutes.
The turnaround time for HLA B27 test or human leukocyte antigen B27 test reports in Bandra may vary depending on the diagnostic centre or lab. Typically, you can expect to receive the results within 24 to 48 hours after the sample is collected and processed.
Ratings & Reviews (0)
Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
WhatsApp