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ASH /NASH / STEATO Profile
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Fasting
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ASH/NASH/STEATO Profile Overview
ASH stands for "alcoholic steatohepatitis." It is a type of liver disease that occurs in people who drink excessive amounts of alcohol. The liver becomes inflamed and filled with fat, leading to liver damage and scarring (cirrhosis).
NASH stands for "nonalcoholic steatohepatitis." It is a type of liver disease that occurs in people who do not drink excessive amounts of alcohol. Instead, it is characterized by the buildup of fat in the liver (steatosis), along with inflammation and liver cell damage. This can lead to cirrhosis. It is more common in individuals with risk factors such as obesity, metabolic syndrome, diabetes, and high triglycerides levels.
Steatohepatitis, is a general term for describing both NASH and ASH as well as other condition characterized by inflammation and fat accumulation in the liver cells.
The ASH/NASH/STEATO Profile is a comprehensive diagnostic test designed to assess liver health and detect conditions related to alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), and other liver disorders characterised by inflammation and fat accumulation in liver cells. This profile is crucial for evaluating the risk of fibrosis (scarring) in the liver, determining the stage of fibrosis, and identifying advanced liver disease.
By measuring various blood markers and biomarkers, the ASH/NASH/STEATO Profile provides valuable insights into liver function and the extent of liver damage. It aids in the diagnosis, monitoring, and management of liver conditions, enabling doctors to develop appropriate treatment plans and monitor disease progression.
Written by: Supriya Kulkarni, Lead-Content & Training
Reasons for Undergoing the ASH/NASH/STEATO Profile
There are several reasons why your doctor may recommend undergoing the ASH/NASH/STEATO Profile:
- To assess the risk of fibrosis (scarring) in the liver
- To identify the stage of fibrosis and determine the severity of liver damage
- To diagnose advanced liver disease
- To monitor the progression of liver conditions over time
- To evaluate individuals experiencing symptoms such as abdominal pain, jaundice, or confusion, which may indicate underlying liver problems
List of Parameters Considered During the ASH/NASH/STEATO Profile
The ASH/NASH/STEATO Profile includes a range of blood tests and biomarkers that provide a comprehensive assessment of liver health:
- Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST): These liver enzymes are elevated in cases of liver damage or inflammation. In NASH, ALT levels are typically higher than AST, while in ASH, the AST/ALT ratio is usually greater than 1.
- Gamma-Glutamyl Transferase (GGT): This enzyme is also elevated in liver disease and can indicate bile duct disorders or excessive alcohol consumption.
- Bilirubin: High levels of bilirubin can suggest jaundice or severe liver dysfunction.
- Albumin: Low albumin levels may indicate poor liver function.
- Platelet Count: A low platelet count can be associated with advanced liver fibrosis or cirrhosis.
- Fibrosis Markers: These biomarkers help assess the degree of liver fibrosis, which is essential for determining the stage of the disease.
ASH/NASH/STEATO Profile Preparation
Preparing for the ASH/NASH/STEATO Profile involves the following steps:
- Medical History Review: Discuss your health conditions, diet, lifestyle, alcohol consumption, and medication use with your healthcare provider.
- Physical Examination: Your doctor will examine your body for signs of liver disease, such as an enlarged liver or spleen, and calculate your body mass index (BMI).
- Blood Sample Collection: A blood sample will be collected using a standard venipuncture procedure. A tourniquet is applied to the upper arm, and the skin is disinfected before the needle is inserted.
ASH/NASH/STEATO Profile Results & Interpretation
The results of the ASH/NASH/STEATO Profile indicate the presence and severity of liver fibrosis and inflammation:
- Fibrosis Stage: The test measures biomarkers that indicate the degree of fibrosis, which can be graded as mild, moderate, or severe.
- Liver Enzymes: Elevated ALT and AST levels suggest liver damage. An AST/ALT ratio greater than 1 is more indicative of ASH, while a ratio less than 1 is more suggestive of NASH.
- Other Biomarkers: High levels of bilirubin, GGT, and other markers can indicate severe liver dysfunction or inflammation.
- Clinical Correlation: The results should be interpreted in conjunction with clinical symptoms, physical examination findings, and imaging studies to determine the overall health of the liver.
Home Collection for ASH/NASH/STEATO Profile Near You
Metropolis Healthcare offers a convenient home sample collection service for the ASH/NASH/STEATO Profile. A trained phlebotomist will come to your doorstep to collect the blood sample, ensuring comfort and safety while maintaining high standards of sample handling and testing accuracy. With timely and reliable results, you can take proactive steps in managing your liver health. Metropolis Healthcare's commitment to accessible healthcare underscores its dedication to providing quality diagnostic solutions conveniently at home.
ASH /NASH / STEATO Profile Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the ASH /NASH / STEATO Profile with a clear pricing structure.
The ASH /NASH / STEATO Profile Price in Mumbai is ₹ 16,800 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
ASH/ NASH/ STEATO Profile is done to evaluate the health of the liver and detect any problems. They can be used to:
- Assess the risk of fibrosis (or scarring) in the liver
- Identify the stage of fibrosis
- Determine if a patient has advanced liver disease
- Monitor the progression of the disease
You should get the ASH/ NASH/ STEATO Profile done if you observe the following symptoms:
- Abdominal pain
- Jaundice
- Confusion
ASH/ NASH/ STEATO Profile is a non-invasive method that measures the levels of specific biomarkers in the blood, which can indicate the presence and severity of liver fibrosis (or scarring) of the liver. The severity of the fibrosis is usually graded as mild, moderate, or severe. Knowing the stage of fibrosis is important as it determines the treatment plan and the need for follow up.
This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer
If the ASH/ NASH/ STEATO Profile is positive, it may indicate the presence of fibrosis (scarring) in the liver. Fibrosis is the formation of excessive fibrous connective tissue in an organ or tissue as a reparative response to injury or disease and is the early stage of liver scarring. In the case of the liver, fibrosis can be caused by a number of different factors, including viral hepatitis, alcohol consumption, non-alcoholic steatohepatitis (NASH), and certain medications.
Associated Tests:
- Fibromax Fibrosis, Activity, STEATO, ASH and NASH of Liver
The ASH/NASH/STEATO Profile is a diagnostic test that evaluates liver health by detecting fibrosis and distinguishing between alcoholic steatohepatitis (ASH) and non-alcoholic steatohepatitis (NASH). It helps assess the risk and stage of liver fibrosis and determines if advanced liver disease is present.
Home sample collection services for the ASH/NASH/STEATO Profile may be available depending on the laboratory or doctor. It is best to confirm with the specific lab or healthcare facility to check if they offer this service.
Normal levels for the ASH/NASH/STEATO Profile vary based on the specific biomarkers measured. Generally, ALT and AST levels should be less than 40 IU/L, bilirubin levels should be less than 1.2 mg/dL, and other markers like albumin and platelet count should be within normal ranges. Fibrosis markers should indicate minimal or no fibrosis in healthy individuals.
The ASH/NASH/STEATO Profile is used to assess the risk and stage of liver fibrosis, determine the presence of advanced liver disease, and monitor disease progression in patients with alcoholic or non-alcoholic steatohepatitis.
The frequency of testing for the ASH/NASH/STEATO Profile depends on individual risk factors and disease progression. Patients with risk factors such as obesity, diabetes, or a history of liver disease may need regular monitoring every 6–12 months.
The ASH/NASH/STEATO Profile can be done at any time, but it is advisable to follow the instructions provided by your doctor regarding fasting and other preparations.
Fasting requirements for the ASH/NASH/STEATO Profile may vary depending on the specific tests included. Consult with your doctor for specific instructions.
Before getting tested for the ASH/NASH/STEATO Profile, inform your doctor about any medications you are taking, follow any dietary or fasting instructions provided, and avoid alcohol consumption for a few days prior to the test if applicable.
The ASH/NASH/STEATO Profile includes blood tests for liver enzymes (ALT, AST, GGT), bilirubin, albumin, platelet count, and fibrosis markers to assess liver health and detect fibrosis.
The ASH/NASH/STEATO Profile should be done when there are symptoms suggestive of liver disease, such as abdominal pain, jaundice, or confusion, or if you have risk factors like obesity, diabetes, or metabolic syndrome.
The blood sample collection for the ASH/NASH/STEATO Profile usually takes only a few minutes. However, the total time spent at the healthcare facility may vary depending on waiting times and administrative procedures.
The turnaround time for ASH/NASH/STEATO Profile reports may vary depending on the laboratory and the complexity of the tests. Typically, results are available within a week depending upon theday/time of sample collection and processing. Check with your doctor or the laboratory for specific timelines.
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