Tryptase Allergy Screening Test

Tryptase Allergy Screening Test is done when:

• There is a severe allergic reaction often referred to as anaphylaxis when localizing symptoms and cause of allergy is not clear. 
• To diagnose mast cell disorders which may cause abnormal activation of the mast cell-mediated functions.
• To monitor the status in patients with mast cell disorders.

The Allergy Screening-Tryptase Test measures the level of a substance called tryptase in your blood. Tryptase is an enzyme released by mast cells, which are immune system cells heavily involved in allergic reactions.

Tryptase screening test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

• An elevated tryptase level can indicate potential issues related to mast cell activation. A significantly elevated tryptase level within a few hours of a severe allergic reaction strongly supports the diagnosis of anaphylaxis. This can be helpful for quick diagnosis and management, especially if the specific allergen is unclear.
• Elevated tryptase can occur in other situations besides anaphylaxis, such as certain mast cell disorders.
• A normal tryptase level doesn't necessarily rule out anaphylaxis. Other factors and tests might be considered for diagnosis.

The healthcare provider may recommend an allergy-screening tryptase test in case a person experiences severe anaphylactic symptoms. These could be troubled breathing, loss of consciousness, hives, etc.

Allergy-screening tryptase test requires a blood sample. An elastic band is used to tighten the upper arm. Also, a person is asked to make a fist. This helps the blood to build up in the veins. A needle is gently inserted into the disinfected skin and the blood sample is slowly drawn into the veil.

There are no specific preparations required for the test. However, it is recommended that you consult with your healthcare provider before taking the test, as they may have specific instructions or recommendations based on your individual medical history and current health status.

Yes, antihistamines can decrease the level of tryptase.

In a normal healthy individual, the tryptase levels are either below or equal to 0-15 ng/ml.

Mast cell disorder is a medical condition in which the immune cells (mast cells) build up under the skin, in the bones, intestine or other organs. Allergy-screening tryptase test is used to detect the condition.

There is no cure for allergies. However, some medications can help relieve the symptoms. Certain allergic screaming tests can help identify the allergens that may be causing an allergic reaction in a person. Avoiding these allergens may help prevent further allergic reactions in the future.

Untreated allergies can get worse. They can cause serious problems. These allergic reactions in the long term can weaken your immune system. This can make your body more susceptible to bacteria, viruses or final infections.

• Tryptase Allergy Test
• Allergy Tryptase Test

Severe allergic symptoms include:

• Swollen throat and tongue
• Troubled breathing
• Rapid heartbeat
• Hives
• Nausea
• Fatigue
• Mental anguish
• Puzzlement
• Dizziness