Thyroid Antibodies Panel (TPOAb and TgAb) in Adyar

• Your doctor may order this test for you if he suspects that you may be suffering from Hashimoto Disease or Grave’s Disease. Symptoms of Hashimoto disease include unexplained weight gain, fatigue, depression, joint pain and low tolerance for cold temperatures. In women, it may also interfere with the menstrual cycle.
• Symptoms of Grave's disease include abnormal building of the eyes, sudden tremors in the hand, insomnia, a goitre and low tolerance for heat. As opposed to Hashimoto’s disease, grave’s disease could lead to weight loss.

This test is ordered for you if you are pregnant to rule out thyroid disorders as thyroid disorders can affect the normal development of fetus. This test is used to diagnose all kinds of autoimmune thyroid diseases.

The Thyroid gland is butterfly shaped and is situated in throat. The thyroid gland produces Thyroxin T4, Triiodothyronine T3 and are extremely important for normal body functioning and metabolism. TSH, i.e, the thyroid stimulating hormone usually stimulates the thyroid gland to produce t3 and t4. A feedback system usually ensures adequate/optimal level of these hormones in the blood. When a patient’s immune system attacks the thyroid gland or proteins related to thyroid, it leads to inflammation of the thyroid and thyroid antibodies are produced. Thyroid antibodies lead to autoimmune conditions like Hashimoto’s Disease and Grave’s Disease. Thyroid antibody tests include: • Thyroid peroxidase antibody (TPO) • Thyroglobulin antibody (TGAb) • Thyroid stimulating hormone receptor antibodies (TSHRAb), including thyroid stimulating immunoglobulin (TSI) and thyroid binding inhibitory immunoglobulin (TBII)