17-Hydroxy Progesterone (Neonatal Screen)

This test measures the levels of 17-Hydroxy Progesterone in newborns. This hormone is vital for the production of cortisol, aldosterone, and sex hormones.

• Detecting congenital adrenal hyperplasia in newborns
• Identifying possible adrenal gland disorders
• Assisting in the early diagnosis and treatment of hormonal imbalances in infants

Doctors recommend this test for:

• Newborns with suspected hormonal issues
• Infants showing signs of adrenal gland disorders
• Babies born into families with a history of congenital adrenal hyperplasia
• Babies displaying symptoms like ambiguous genitalia or salt-wasting

Abnormal results may indicate congenital adrenal hyperplasia, adrenal gland dysfunction, or other hormonal imbalances. Follow-up tests and consultation with a specialist may be necessary for further evaluation and treatment planning.

During this test:

• A small drop of blood is collected from a heel or finger prick on a special filter paper.
• The sample is dried for at least three hours before testing.
• The procedure is quick and relatively painless for newborns.

Before the test:

• No specific fasting is required.
• Ensure a relevant clinical history is provided.
• Stop any amino acid supplements or medications as per the doctor's advice.

Other related tests include:

• Plasma, LCMS, or GCMS confirmation for positive cases
• Additional enzyme assay tests for metabolic disorders
• Further workup for abnormal results may be needed.

• 17-OHP neonatal screen
• Congenital adrenal hyperplasia screening
• Newborn congenital adrenal hyperplasia screening

Congenital adrenal hyperplasia is a genetic disorder affecting hormone production by the adrenal glands. It often leads to imbalances in cortisol and aldosterone levels, causing symptoms like ambiguous genitalia in newborns. It can later result in various health issues, including abnormal sexual development, electrolyte imbalances, and potentially life-threatening adrenal crises.