Beta-D-Glucan Level by Protease Zymogen Colorimetry

This test measures the levels of Beta-D-Glucan in your blood.

This test is mainly done to diagnose invasive fungal infections. It helps in identifying the presence of these infections so that appropriate treatment can be initiated. Early detection is important to prevent complications associated with fungal infections.

Your doctor might recommend this test if you have symptoms suggestive of invasive fungal infections, such as persistent fever, unexplained weight loss, fatigue, or respiratory issues. Patients with compromised immune systems, such as those undergoing chemotherapy or organ transplantation, may also need this test for early detection.

Elevated levels may indicate the presence of invasive fungal infections, which can be serious if left untreated.

During this test, a small sample of your blood will be collected for analysis. The process is quick and relatively painless, involving a simple blood draw.

There are no specific preparations required for this test. However, it is important to inform your doctor about any medications you are taking, as some medications can interfere with the test results. Follow any instructions provided by your doctor regarding fasting or discontinuing certain medications. Please reach out to your healthcare provider for any specific requirements.

Other tests that may be ordered alongside this test include fungal cultures, PCR tests for specific fungal pathogens, and imaging studies such as CT scans or X-rays to assess the extent of infection or identify the affected area of the body.

Serum Beta-D-Glucan Test, Fungal Biomarker Test

Invasive fungal infections are serious infections caused by certain types of fungi that can invade various parts of the body, including the lungs, bloodstream, and organs. These infections can be life-threatening, especially in individuals with weakened immune systems. Early detection is crucial for effective treatment.

The Beta D Glucan test is a blood test that measures the levels of (1→3)-β-D-glucan, a component of fungal cell walls, in your bloodstream. It helps detect and diagnose invasive fungal infections, such as candidiasis or aspergillosis.

Yes, home sample collection is available for the Beta D Glucan test. A highly trained phlebotomist will collect your blood sample in the comfort of your own home. 

Normal levels for the Beta D Glucan test are:

• Negative: Less than 60 pg/mL, indicating no significant fungal infection.
• Intermediate: 60-79 pg/mL, which may require further investigation.
• Positive: 80 pg/mL or higher, suggesting the presence of a fungal infection.

The Beta D Glucan test is used to diagnose invasive fungal infections, particularly in high-risk patients such as those with weakened immune systems. It also helps monitor the effectiveness of antifungal treatments and aids in early detection of fungal infections.

The frequency of Beta D Glucan testing depends on your clinical condition and your doctor's recommendation. High-risk patients may require more frequent testing, while others may need the test only when there's a suspicion of fungal infection.

There is no specific time recommendation for the Beta D Glucan test. Your doctor will advise you on when to get the test done based on your symptoms, medical history, and other clinical factors.

No, fasting is not required for the Beta D Glucan test. You can eat and drink normally before the test unless your doctor provides specific instructions.

Before Beta D Glucan test, inform your doctor about any medications or supplements you're taking, as some may interfere with the test results. Also, avoid recent infusions of IVIG or albumin, and certain medical procedures like haemodialysis.

The Beta D Glucan test measures concentration of (1→3)-β-D-glucan in picograms per millilitre (pg/mL) in serum, plasma, bronchoalveolar lavage (BAL) fluid, or cerebrospinal fluid (CSF) samples.

The Beta D Glucan test should be done when there's a clinical suspicion of an invasive fungal infection, especially in high-risk patients such as those with haematological malignancies, organ transplant recipients, or critically ill individuals.

The Beta D Glucan test procedure itself takes around 90 minutes, including pretreatment and measurement steps. However, the overall process from sample collection to reporting may take about a week.

Typically, you can expect to receive the Beta D Glucan test reports within 24 hours based on the date/time when the sample is collected and processed. However, this may vary depending on the lab and other factors.